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diagnosis rheumatology differential management sle algorithm classification erythematosus systemic acr2021 antibodies dermatology granulomatosis guidelines inflammatory pulmonary renal summary syndrome syndromes
ANA (Antinuclear Antibody) and ANCA (Antineutrophil cytoplasmic antibodies) • Systemic lupus erythematosus 1. Anti-dsDNA
) • Systemic lupus ... Vasculitis: • ... Renal-limited vasculitis ... antibodies #diagnosis #rheumatology ... #diseases
ANCA-Associated Vasculitis A group of necrotizing, small-vessel vasculitis without immune complex deposition. Complement levels are normal due
ANCA-Associated ... Vasculitis A group ... , small-vessel vasculitis ... PR3 Anti-GBM disease ... PR3 #Diagnosis #Rheumatology
Pulmonary Renal Syndrome Definition: Diffuse alveolar hemorrhage + Glomerulonephritis Presentation (Pulmonary and renal manifestations can occur weeks apart):
vasculitis (Eosinophilic ... , Microscopic polyangiitis ... vasculitis (IgA-associated ... vasculitis, Behcet ... Complex: Systemic lupus
Classification of Vasculitis Vasculitis of large vessels - Arteritis temporalis (giant-cell arteritis) - Takayasu
Vasculitis of ... small vessels - ANCA-associated ... - microscopic polyangiitis ... - systemic lupus ... Vessels #Diagnosis #Rheumatology
Granulomatosis with Polyangiitis (GPA) and Microscopic Polyangiitis (MPA) - ANCA Vasculitis Management Algorithm - ACR/VF 2021
and Microscopic Polyangiitis ... (MPA) - ANCA Vasculitis ... #MPA #ANCA #Vasculitis ... #Management #Treatment ... Guidelines #algorithm #rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
• Microscopic Polyangiitis ... inflammation Others: • Lupus ... Vasculitis: + MPO-ANCA ... such as systemic lupus ... differential #diagnosis #rheumatology
Autoantibodies and their Disease Associations ANA - Non-specific; common in SLE, autoimmune hepatitis Anti-CCP, Rheumatoid factor - RA Anti-dsDNA
c-ANCA - Vasculitis ... granulomatosis p-ANCA ... - Vasculitis, e.g ... Microscopic polyangiitis ... diagnosis #table #rheumatology
Eosinophilic Granulomatosis with Polyangiitis (EGPA) - ANCA Vasculitis Management Algorithm - ACR/VF 2021 Guidelines • Active
Granulomatosis with Polyangiitis ... (EGPA) - ANCA Vasculitis ... Granulomatosis #Polyangiitis ... #ANCA #Vasculitis ... #Management #Treatment
Vasculitis Involving the Skin - Differential Diagnosis Framework Primary: 50% Cutaneous Vasculitis: Leukocytoclastic Vasculitis Secondary: CTD: SLE, RA
• ANCA Associated ... - Microscopic polyangiitis ... : • Behcet Disease ... #skin #dermatology ... #rheumatology #
Rapidly Progressive Glomerulonephritis (RPGN) RPGN has three primary pathophysiologic causes differentiated by immunofluorescence Immune Complex Mediated (granular staining):
Post-strep GN, Lupus ... involvement: Anti-GBM Disease ... (C-ANCA): GPA > ... Glomerulonephritis #Vasculitis ... diagnosis #algorithm #rheumatology
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