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diagnosis differential rheumatology disorders erythematosus lupus management neurology systemic autoimmune complications cord hematology lymphomas lymphoproliferative musculoskeletal myelitis myopathy nonhodgkin sams
Systemic Lupus Erythematosus (SLE): Musculoskeletal Manifestations • Immune Complex Deposition - Arthralgia, Arthritis
Erythematosus (SLE ... - Myositis ... #MSK #Musculoskeletal ... Complications #pathophysiology ... #signs #symptoms
Autoimmune Myositis Necrotizing myopathy is associated with higher CK levels, greater level of muscle weakness, less systemic
Autoimmune Myositis ... associated with higher CK ... greater level of muscle ... less systemic symptoms ... Can also see mechanics
Statin Induced Muscle Toxicity - Summary Clinical Presentation: • Elevations of serum creatine kinase with proximal myalgia
Symptoms (SAMS) ... • Myalgia • Myositis ... erythematosus (SLE ... inclusion body myositis ... Diagnosis: • CK
Spinal Cord Disorders - Differential Diagnosis Framework Spinal cord neurological lesion: Clinical findings: • Symptoms and signs below
findings: • Symptoms ... Hyperreflexia - Muscle ... - Transverse myelitis ... Behcet disease - SLE ... differential #algorithm
Transverse Myelitis Overview Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
10-33% develop MS ... monophasic Pathophysiology ... Bilateral signs and/or symptoms ... Evaluate for NMO, SLE ... Disorders: - SLE
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
Differential Diagnosis Algorithm ... pattern of spread, B symptoms ... Amy Chung, MD, MSc ... Lymphoproliferative #Disorders #Classification ... #pathophysiology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... Skin Disease Classification ... erythematosus (SCLE ... • Transverse Myelitis ... Induced Lupus: • Symptoms
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
Joints: myalgia and muscle ... Conjunctivitis, mucositis ... Presentation - Systemic Symptoms ... vasculitis, and SLE ... #rheumatology #classification
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