36 results
diagnosis differential management neurology rheumatology treatment clinical pathophysiology signs syndrome algorithm cord erythematosus gravis lupus myasthenia myopathy orthopedics ossificans pain
Autoimmune Myositis Necrotizing myopathy is associated with higher CK levels, greater level of muscle weakness, less systemic
Autoimmune Myositis ... associated with higher CK ... greater level of muscle ... less systemic symptoms ... @AnnKumfer #Autoimmune
Systemic Lupus Erythematosus (SLE): Musculoskeletal Manifestations • Immune Complex Deposition - Arthralgia, Arthritis
- Myositis ... Weakness, Incr CK ... Myopathy (Also caused ... Erythematosus #SLE #MSK ... pathophysiology #signs #symptoms
Creatine Kinase - Causes of Elevated CK Levels Acute CK Elevation (Pain > Weakness): • RHABDOMYOLYSIS
Creatine Kinase - Causes ... Subacute to Chronic Causes ... ): • PROXIMAL MUSCLE ... myopathy - Autoimmune ... Inclusion body myositis
Statin Induced Muscle Toxicity - Summary Clinical Presentation: • Elevations of serum creatine kinase with proximal myalgia
Symptoms (SAMS) ... symptoms: weeks ... • Myalgia • Myositis ... inclusion body myositis ... Diagnosis: • CK
Autoimmune Myositis - Differential Diagnosis Framework Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
Autoimmune Myositis ... Tests: • Measure CK ... (symmetric) • CK ... weakness • CK ... statins - probably caused
Chronic Joint Pain - Differential Diagnosis Algorithm Intra-Articular - Bone • Stress
Fasciitis) - Muscle ... Delayed Onset Muscle ... Fibromyalgia • Myositis ... Intraarticular #MSK ... #Orthopedics #Causes
Neuromyelitis Optica (NMO) - Clinical Manifestations • Optic neuritis: Reduced visual acuity, ranging from mild to
involvement: Intractable nausea ... • Transverse myelitis ... positive NMO only): Myositis ... , Comorbid autoimmune ... diagnosis #neurology #symptoms
Causes of Neuromuscular Weakness • Spinal Cord: Demyelinating Disease (MS), Epidural abscess, Infarction, Syringomyelia, Tetanus, Transverse
Causes of Neuromuscular ... Demyelinating Disease (MS ... Tetanus, Transverse Myelitis ... aminoglycosides) • Muscles ... Neuromuscular #Weakness #Causes
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary Causes of Rhabdomyolysis: • Trauma: - Immobilization - Crush injury - Compartment
Management Summary Causes ... Hyperthyroidism - Autoimmune ... : • Triad of symptoms ... urine • Other symptoms ... Diagnosis #Management #causes
Spinal Cord Disorders - Differential Diagnosis Framework Spinal cord neurological lesion: Clinical findings: • Symptoms and signs below
findings: • Symptoms ... Hyperreflexia - Muscle ... equina- decreased muscle ... Non-compressive Spinal Cord Causes ... - Transverse myelitis
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