37 results
differential signs pathophysiology causes orthopedics syndrome clinical disorders hypothyroid management myopathy neurology rheumatology adrenal autoimmune hyperthyroidism intraarticular joint myositis peripheral
Systemic Lupus Erythematosus (SLE): Musculoskeletal Manifestations • Immune Complex Deposition - Arthralgia, Arthritis
Weakness, Normal CK ... Weakness, Incr CK ... Erythematosus #SLE #MSK ... pathophysiology #signs #symptoms ... #diagnosis
Hypothyroid Myopathy Very common (up to 80% ) in patients with hypothyroidism Pathophysiology: • T4 deficiency leads to
which impairs musde ... Asymptomatic CK ... proximal myopathy → Muscle ... pathophysiology #signs #symptoms ... #endocrinology
Causes of Peripheral Weakness - With and Without Sensory Changes - Differential Diagnosis Algorithm With Sensory Changes:
- Differential Diagnosis ... Algorithm With ... Myopathy - Proximal muscle ... involvement, elevated CK ... #Algorithm #Causes
Statin Induced Muscle Toxicity - Summary Clinical Presentation: • Elevations of serum creatine kinase with proximal myalgia
Symptoms (SAMS) ... symptoms: weeks ... Atorvastatin Diagnosis ... : • CK: - SAMS ... toxicity #myopathy #diagnosis
Radiculopathy: Signs and Symptoms • Back/Neck Pain • Decr Range of motion • Abnormal posturing •
Radiculopathy: Signs and Symptoms ... can happen) • Muscle ... reflexes (at those muscles ... Radiculopathy #MSK ... #diagnosis #signs
Hyperthyroidism – symptoms and signs. Symptoms: Weight loss, Increased appetite, Irritability/behaviour change, Restlessness, Malaise, Stiffness, Muscle weakness,
Symptoms: Weight ... Malaise, Stiffness, Muscle ... myopathy, Proximal muscle ... #Signs #Diagnosis ... #Endocrinology
Cushing Syndrome Testing Algorithm INDICATIONS FOR TESTING: • Suspected Cushing syndrome (central obesity, muscle weakness, refractory hypertension) Testing:
Syndrome Testing Algorithm ... central obesity, muscle ... Urine Free by LC-MS ... Cushing #Syndrome #diagnosis ... #algorithm #endocrinology
Autoimmune Myositis Necrotizing myopathy is associated with higher CK levels, greater level of muscle weakness, less systemic
associated with higher CK ... greater level of muscle ... less systemic symptoms ... /full triad at diagnosis ... Autoimmune #Myositis #diagnosis
Causes of Peripheral Weakness without Sensory Changes - Differential Diagnosis Algorithm No Objective Weakness • Cardio-pulmonary disease
- Differential Diagnosis ... Algorithm No Objective ... Myopathy - Proximal muscle ... involvement, elevated CK ... #Algorithm #Causes
Graves’ Disease: Pathogenesis and Clinical Findings B & T lymphocyte mediated autoimmunity attack TSH receptor -> Continuous
etiology Signs/Symptoms ... proptosis - Muscle ... pathophysiology #endocin #endocrinology ... #symptoms #signs ... #diagnosis
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