192 results
signs differential pathophysiology management neurology rheumatology causes clinical syndrome algorithm orthopedics treatment radiology disease endocrinology mri complications lupus psychiatry workup
Myositis and Myopathies Polymyositis • Progressive, symmetric muscle weakness • Elevated CK, +Anti-Jo, +Anti-Mi2 Dermatomyositis
Progressive, symmetric muscle ... weakness • Elevated CK ... rash • Elevated CK ... mildly elevated CK ... #differential #diagnosis
Systemic Lupus Erythematosus (SLE): Musculoskeletal Manifestations • Immune Complex Deposition - Arthralgia, Arthritis
Weakness, Normal CK ... Weakness, Incr CK ... Erythematosus #SLE #MSK ... pathophysiology #signs #symptoms ... #diagnosis
Giant Cell (Temporal) Arteritis: Pathogenesis and investigations Risk Factors: - Unclear environmental triggers (may be viral, not
old; F>M Signs/Symptoms ... skin lesions - Muscle-soreness ... Pathophysiology #Diagnosis ... #Signs #Symptoms ... #Vasculitis
Myositis and Myopathies #ESR #CK #Differential diagnosis of myopathy #Inflammatory #myopathies #Dermatomyositis #muscle weakness #Polymyositis #Inclusion body myositis #Polymyalgia rheumatica #Fibromyalgia #Hypothyroid myopathy #Muscle stiffness #Drug-induced
Myopathies #ESR #CK ... #Differential diagnosis ... Dermatomyositis #muscle ... Hypothyroid myopathy #Muscle ... Cocaine-induced myopathy #Muscle
Dermatomyositis (DM) and Polymyositis (PM): Pathogenesis and clinical findings Elevated Antinuclear Antibodies: Anti-Jo-1, Anti-OJ, Anti-Mi2, Anti-SRP, Anti-EJ,
- Elevation of muscle ... Creatinine kinase (CK ... Polymyositis #PM #Diagnosis ... Pathophysiology #Signs #Symptoms ... #Vasculitis
Creatine kinase (CK) is an intracellular enzyme present in skeletal muscle, myocardium & brain; smaller amounts
present in skeletal muscle ... of underlying muscle ... The definitive diagnosis ... , confirms the diagnosis ... useful marker of muscle
Statin Induced Muscle Toxicity - Summary Clinical Presentation: • Elevations of serum creatine kinase with proximal myalgia
Symptoms (SAMS) ... symptoms: weeks ... Atorvastatin Diagnosis ... : • CK: - SAMS ... toxicity #myopathy #diagnosis
Creatine Kinase - Causes of Elevated CK Levels Acute CK Elevation (Pain > Weakness): • RHABDOMYOLYSIS
Causes of Elevated CK ... Levels Acute CK ... ): • PROXIMAL MUSCLE ... Kinase #Elevated #CK ... #differential #diagnosis
Radiculopathy: Signs and Symptoms • Back/Neck Pain • Decr Range of motion • Abnormal posturing •
Radiculopathy: Signs and Symptoms ... can happen) • Muscle ... reflexes (at those muscles ... Radiculopathy #MSK ... #diagnosis #signs
Autoimmune Myositis Necrotizing myopathy is associated with higher CK levels, greater level of muscle weakness, less systemic
associated with higher CK ... greater level of muscle ... less systemic symptoms ... /full triad at diagnosis ... Autoimmune #Myositis #diagnosis
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