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diagnosis rheumatology disorders autoimmune classification lupus myositis pathophysiology sle vasculitis arthropathies arthropathy complications cord joint lymphomas lymphoproliferative management monoarthritis monoarticular
Systemic Lupus Erythematosus (SLE): Musculoskeletal Manifestations • Immune Complex Deposition - Arthralgia, Arthritis
Systemic Lupus Erythematosus ... femoral heads • Myopathy ... #Lupus #Erythematosus ... #SLE #MSK #Musculoskeletal ... pathophysiology #signs #symptoms
Statin Induced Muscle Toxicity - Summary Clinical Presentation: • Elevations of serum creatine kinase with proximal myalgia
Symptoms (SAMS) ... syndrome (GBS), systemic ... lupus erythematosus ... syndrome (LEMS), systemic ... Diagnosis: • CK
Autoimmune Myositis Necrotizing myopathy is associated with higher CK levels, greater level of muscle weakness, less systemic
Myositis Necrotizing myopathy ... associated with higher CK ... greater level of muscle ... weakness, less systemic ... symptoms, and less
Joint Disorders - Differential Diagnosis Algorithm Monoarthritis • Septic • Crystalline - Gout
Joint Disorders - Differential ... Diagnosis Algorithm ... Lupus Erythematosus ... should have other symptoms ... Joint #Disorders #msk
Spinal Cord Disorders - Differential Diagnosis Framework Spinal cord neurological lesion: Clinical findings: • Symptoms and signs below
Cord Disorders - Differential ... findings: • Symptoms ... , Scleroderma, Systemic ... diagnosis #neurology #differential ... #algorithm
Autoimmune Myositis - Differential Diagnosis Framework Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
Autoimmune Myositis - Differential ... (symmetric) • CK ... • Conduction system ... #rheumatology # ... differential #diagnosis
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... (SCLE): • Photosensitive ... permanent alopecia Differential ... vein thrombosis Hematologic ... Induced Lupus: • Symptoms
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
Diagnosis Algorithm ... pattern of spread, B symptoms ... Amy Chung, MD, MSc ... pathophysiology #Hematology ... #algorithm
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
Vasculitides - Differential ... ischemia - Skin: erythematous ... Joints: myalgia and muscle ... lupus erythematosus ... Symptoms (Sx) in
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
Vasculitis - Differential ... Symptoms (SX) in ... ischemia • Skin: Erythematous ... • Progressive symptoms ... #Diagnosis #Rheumatology
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