84 results
Systemic Lupus Erythematosus (SLE): Musculoskeletal Manifestations

 • Immune Complex Deposition
    - Arthralgia, Arthritis
Systemic Lupus Erythematosus ... Weakness, Incr CK ... Osteoporosis #Systemic ... Erythematosus #SLE #MSK ... pathophysiology #signs #symptoms
Myositis and Myopathies
Polymyositis 
 • Progressive, symmetric muscle weakness 
 • Elevated CK, +Anti-Jo, +Anti-Mi2
Dermatomyositis
weakness • Elevated CK ... rash • Elevated CK ... mildly elevated CK ... Myopathies #myopathy #differential ... diagnosis #comparison #rheumatology
Autoimmune Myositis
Necrotizing myopathy is associated with higher CK levels, greater level of muscle weakness, less systemic
associated with higher CK ... greater level of muscle ... weakness, less systemic ... symptoms, and less ... Myositis #diagnosis #rheumatology
Approach to Leukocytosis - Differential Diagnosis Algorithm

Features of hematologic malignancy:
 • Symptoms: B-symptoms, bruising/bleeding, fatigue/weakness, immunosuppression
Leukocytosis - Differential ... Diagnosis Algorithm ... malignancy: • Symptoms ... : B-symptoms, bruising ... #hematology #WBC
Joint Disorders - Differential Diagnosis Algorithm
Monoarthritis
 • Septic
 • Crystalline
     - Gout
Joint Disorders - Differential ... Diagnosis Algorithm ... should have other symptoms ... Joint #Disorders #msk ... #Differential #
Causes of Peripheral Weakness - With and Without Sensory Changes - Differential Diagnosis Algorithm
With Sensory Changes:
Sensory Changes - Differential ... Diagnosis Algorithm ... Myopathy - Proximal muscle ... involvement, elevated CK ... #Diagnosis #Algorithm
Nail Disorders - Primary and Systemic Causes - Differential Diagnosis Algorithm

#NailDisorders #Primary #Secondary #Systemic #dermatology #Differential
- Primary and Systemic ... Causes - Differential ... Diagnosis Algorithm ... #dermatology #Differential ... #Diagnosis #Algorithm
Statin Induced Muscle Toxicity - Summary

Clinical Presentation:
 • Elevations of serum creatine kinase with proximal myalgia
Symptoms (SAMS) ... symptoms: weeks ... syndrome (GBS), systemic ... syndrome (LEMS), systemic ... Diagnosis: • CK
Approach to Low Back Pain - Differential Algorithm
- Non-MSK
- Axial / Musculoskeletal
- Radicular
- Systemic Disease (Do
Low Back Pain - Differential ... Algorithm - Non-MSK ... - Radicular - Systemic ... #LowBackPain #Differential ... #Algorithm #Causes
Diagnostic Schema for Hyperferritinemia

Pearl: Diseases associated with extreme elevations: 
1. HLH 
2. Still's disease 
3. Systemic
Systemic histoplasmosis ... Hyperferritinemia #Algorithm ... #Differential # ... Diagnosis #Hematology