9 results
Systemic Lupus Erythematosus (SLE): Musculoskeletal Manifestations

 • Immune Complex Deposition
    - Arthralgia, Arthritis
Systemic Lupus Erythematosus ... 80%) - Proximal Weakness ... femoral heads • Myopathy ... Erythematosus #SLE #MSK ... pathophysiology #signs #symptoms
Statin Induced Muscle Toxicity - Summary

Clinical Presentation:
 • Elevations of serum creatine kinase with proximal myalgia
proximal myalgia and weakness ... weakness • Soreness ... syndrome (GBS), systemic ... syndrome (LEMS), systemic ... Diagnosis: • CK
Causes of Peripheral Weakness - With and Without Sensory Changes - Differential Diagnosis Algorithm
With Sensory Changes:
Sensory Changes - Differential ... Diagnosis Algorithm ... Oculomotor • Myopathy ... - Proximal muscle ... involvement, elevated CK
Autoimmune Myositis
Necrotizing myopathy is associated with higher CK levels, greater level of muscle weakness, less systemic
Myositis Necrotizing myopathy ... associated with higher CK ... greater level of muscle ... weakness, less ... systemic symptoms
Causes of Peripheral Weakness without Sensory Changes - Differential Diagnosis Algorithm
No Objective Weakness
 • Cardio-pulmonary disease
Sensory Changes - Differential ... Diagnosis Algorithm ... • Congenital Myopathy ... - Proximal muscle ... involvement, elevated CK
Spinal Cord Disorders - Differential Diagnosis Framework

Spinal cord neurological lesion:
Clinical findings:
 • Symptoms and signs below
Cord Disorders - Differential ... findings: • Symptoms ... , Scleroderma, Systemic ... diagnosis #neurology #differential ... #algorithm
Autoimmune Myositis - Differential Diagnosis Framework

Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
Autoimmune Myositis - Differential ... weakness • CK ... weakness PE: Muscle ... • Conduction system ... #rheumatology #differential
Polymyalgia Rheumatica (PMR) Diagnosis and Management Summary

WHAT?
 • Polymyalgia rheumatica (PMR) is a common systemic inflammatory
PMR) is a common systemic ... motion and no weakness ... • An evaluation ... Also consider an evaluation ... normal and can help differentiate
Evaluation of Recurrent Falls

Core Concept:
Maintaining an upright posture requires the integrated function of multiple systems.
Disruption in
Evaluation of Recurrent ... presyncope, exertional symptoms ... • Clues: Focal weakness ... , muscle wasting ... Falls #Diagnosis #Differential