19 results
Systemic Lupus Erythematosus (SLE): Musculoskeletal Manifestations

 • Immune Complex Deposition
    - Arthralgia, Arthritis
Systemic Lupus Erythematosus ... femoral heads • Myopathy ... Osteoporosis #Systemic ... Erythematosus #SLE #MSK ... pathophysiology #signs #symptoms
Statin Induced Muscle Toxicity - Summary

Clinical Presentation:
 • Elevations of serum creatine kinase with proximal myalgia
Symptoms (SAMS) ... symptoms: weeks ... syndrome (GBS), systemic ... syndrome (LEMS), systemic ... Diagnosis: • CK
Autoimmune Myositis
Necrotizing myopathy is associated with higher CK levels, greater level of muscle weakness, less systemic
Myositis Necrotizing myopathy ... associated with higher CK ... greater level of muscle ... weakness, less systemic ... symptoms, and less
Hypothyroid Myopathy
Very common (up to 80% ) in patients with hypothyroidism
Pathophysiology:
 • T4 deficiency leads to
Hypothyroid Myopathy ... which impairs musde ... Asymptomatic CK ... → Muscle hypertrophy ... pathophysiology #signs #symptoms
Causes of Peripheral Weakness - With and Without Sensory Changes - Differential Diagnosis Algorithm
With Sensory Changes:
Differential Diagnosis Algorithm ... Oculomotor • Myopathy ... - Proximal muscle ... involvement, elevated CK ... Differential #Diagnosis #Algorithm
Myelopathy - Injury to the entire spinal cord - Signs and Symptoms
 • Ataxia (early sign)
Myelopathy - Injury ... cord - Signs and Symptoms ... Hypertonicity (muscles ... diagnosis #signs #symptoms ... #msk
Causes of Peripheral Weakness without Sensory Changes - Differential Diagnosis Algorithm
No Objective Weakness
 • Cardio-pulmonary disease
Differential Diagnosis Algorithm ... • Congenital Myopathy ... - Proximal muscle ... involvement, elevated CK ... Differential #Diagnosis #Algorithm
Hyperthyroidism – symptoms and signs. 

Symptoms:

Weight loss, Increased appetite, Irritability/behaviour change, Restlessness, Malaise, Stiffness, Muscle weakness,
Symptoms: Weight ... Malaise, Stiffness, Muscle ... peripheries, Systolic ... loss, Proximal myopathy ... , Proximal muscle
Joint Disorders - Differential Diagnosis Algorithm
Monoarthritis
 • Septic
 • Crystalline
     - Gout
Differential Diagnosis Algorithm ... Lupus - with Systemic ... should have other symptoms ... Joint #Disorders #msk ... Differential #Diagnosis #Algorithm
Anterior Shoulder Dislocation: Pathogenesis, clinical, and radiographic findings

Trauma, Fall on, outstretched arm, Overhead throwing => Abduction
tensile strength of muscle ... damage to nerves, muscles ... Diagnosis #signs #symptoms ... #msk #orthopedics