47 results
Systemic Lupus Erythematosus (SLE): Musculoskeletal Manifestations

 • Immune Complex Deposition
    - Arthralgia, Arthritis
Systemic Lupus Erythematosus ... Weakness, Incr CK ... Osteoporosis #Systemic ... Erythematosus #SLE #MSK ... pathophysiology #signs #symptoms
Autoimmune Myositis
Necrotizing myopathy is associated with higher CK levels, greater level of muscle weakness, less systemic
Autoimmune Myositis ... associated with higher CK ... greater level of muscle ... weakness, less systemic ... symptoms, and less
Joint Disorders - Differential Diagnosis Algorithm
Monoarthritis
 • Septic
 • Crystalline
     - Gout
Inflammatory Bowel Disease ... autoimmune disease ... Lupus - with Systemic ... should have other symptoms ... Joint #Disorders #msk
Antinuclear Antibodies (ANA)
ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
Positive ANA ≠ Autoimmune ... Disease! ... context of other symptoms ... Disorders, Infection, Autoimmune ... Thyroid, Autoimmune
BEE Syndromes - Immune-mediated conditions affecting the brain, eye, and ear

Visual or auditory symptoms in conjunction
Visual or auditory symptoms ... conjunction with symptoms ... central nervous system ... an underlying autoimmune ... Sjögren syndrome • Systemic
Statin Induced Muscle Toxicity - Summary

Clinical Presentation:
 • Elevations of serum creatine kinase with proximal myalgia
Symptoms (SAMS) ... symptoms: weeks ... syndrome (GBS), systemic ... syndrome (LEMS), systemic ... Diagnosis: • CK
Systemic Sclerosis (Scleroderma)
Multi-system autoimmune disease characterized by vasculopathy and progressive fibrosis of skin and internal organs
3
Systemic Sclerosis ... autoimmune disease ... thickening Signs and Symptoms ... interstitial lung disease ... diagnosis #signs #symptoms
Castleman's Disease and Associated Syndromes
HYALINE VASCULAR VARIANT
 • unicentric, HHV8-ve, children and young.
 • Hyalinized vessels
Dysplastic FDC • Systemic ... symptoms usually ... unicentric • Systemic ... symptoms usually ... Plasmablastic variant" Autoimmune
Autoimmune Myositis - Differential Diagnosis Framework

Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
Autoimmune Myositis ... Tests: • Measure CK ... (symmetric) • CK ... weakness • CK ... • Conduction system
Primary Sjogren’s Syndrome: Pathogenesis and Clinical Findings
• Primary Sjögren's is a solitary process whereas secondary Sjögren's
accompanies other autoimmune ... diseases • In ... (PBC), or with systemic ... diseases like rheumatoid ... (SLE) Signs / Symptoms