17 results
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Lymphohistiocytosis (HLH ... cytokines (TNFa,lL1, IL6 ... • Clinical: fever ... Drugs, Unknown cause ... 100 mg/m2) : in case
Step by Step Algorithmic Approach to Pediatric Fever

Age < 21 days old (or 28 days for
Step by Step Algorithmic ... Approach to Pediatric Fever ... Age < 21 days old ... Procalcitonin >= 0.5 ng/mL ... #Infant #Fever
Intestinal Manifestations of HIV, IBD in HIV - IBD Algorithm

HIV + IBD Background
HIV + IBD Treatment
Intestinal
in HIV - IBD Algorithm ... HIV + IBD Treatment ... cryptosporidium • <100: CMV ... #Algorithm #diagnosis ... gastroenterology #IBDAlgorithm
ID Approach to Fever and Rash - Diagnostic Algorithm
Central Maculopapular (most common):
Measles, Parvovirus 819 / EBV,
ID Approach to Fever ... Rash - Diagnostic Algorithm ... Secondary syphilis, EM ... Washington University ID ... Febrile #Diagnosis #Algorithm
Causes of Thrombocytopenia - Differential Diagnosis Algorithm
 
Decreased Megakaryopoiesis
 • Aplastic Anemia
 • Toxic Damage (e.g.
Causes of Thrombocytopenia ... Differential Diagnosis Algorithm ... ITP • SLE • CLL ... Alloimmune • anti-HLA ... #Causes #Hematology
Differential Diagnosis for Generalized Lymphadenopathy

Viral
• HIV 
• EBV 
• CMV 
• HBV 
• Dengue 
• Rubella
HIV • EBV • CMV ... Amyloidosis • HLH ... Differential #Diagnosis #Causes ... #Algorithm #Oncology
Causes of Fever of Unknown Origin (FUO) - Differential Diagnosis Algorithm
Neoplasm:
• NHL
• Hodgkin's lymphoma
• Leukemia
• Solid
Causes of Fever ... Differential Diagnosis Algorithm ... HIV • EBV • CMV ... Differential #Diagnosis #Algorithm ... #causes
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
lymphohistiocytosis (HLH ... disease • Periodic fever ... multiorgan failure • Fever ... - Nonremitting fever ... 5000 to 10,000 ng/mL
Algorithmic Approach to Acute Interstitial Nephritis
When to suspect AIN? (not sensitive)
 • AKI, AKD, rapidly progressive
Algorithmic Approach ... triad (<10%): fever ... sterile pyuria, WBC casts ... microscopic hematuria, mild ... Nephritis #AIN #Algorithm
Upper and Lower Causes of GI Bleed
Upper:
 • Esophagus: Tear (Mallory Weiss, Boerhaave syndrome), Variceal, Esophagitis,
Upper and Lower Causes ... colitis, UC/Chrons (IBD ... , Radiation CMC ... differential #diagnosis #Causes ... #algorithm