18 results
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
CNS Manifestations ... Demyelinating Syndrome ... Erythematosus #SLE #CNS ... cerebritis #diagnosis #management ... #treatment
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
basal ganglia, CNS ... meningitis), MCC CNS ... Arthritis, AS Treatment ... collaboration • CNS ... #diagnosis #management
Candidemia Workup and Management - IDSA Guidelines
1) Antibiotics
 • Empiric: Echinocandins (e.g. micafungin) for most patients
Candidemia Workup and Management ... Consider: Spine, CNS ... IDSA #Guidelines #Management ... #candidiasis #treatment ... #fungal #fungemia
Adie's Pupil
What? Unknown nature & benign
 • Regular and mildly dilated pupil (4-6mm);
 • Light-near dissociaton;
Holmes-Adie Syndrome ... Diagnosis: • CN ... #Adies #Pupil #PhysicalExam ... #neurology #ophthalmology
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
Macrophage Activation Syndrome ... nervous system (CNS ... Treatment: • Corticosteroids ... #Diagnosis #Management ... #Hematology #Rheumatology
Causes of Antibiotic Failure - Differential Diagnosis Framework
Diagnosis:
 • Non-Infectious: Malignant, Autoimmune, Drug-related (NMS, serotonin syndrome,
NMS, serotonin syndrome ... bacteria: Viral, Fungal ... Immunocompromise Treatment ... Tissue penetration (CNS ... • Secondary to Treatment
Sjogren's Syndrome Overview

Epidemiology:
• F > M: 9:1
• 5-6th Decades (can be any age)

Autoimmune exocrinopathy multisystemic disease
Parotid swelling CNS ... nervous system (CNS ... • 8%-27% for CNS ... Adenocarcinoma Treatment ... Diagnosis #Management
Invasive Aspergillus (IA) - Diagnosis and Management
Aspergillus is ubiquitous in nature. Most invasive infections are caused
Diagnosis and Management ... Rhinosinusitis, CNS ... this morphology Treatment ... IA #Diagnosis #Management ... #treatment #fungal
Mycoses

HISTOPLASMOSIS
• Inhalation of conidia → Yeast → travel to lymph nodes → spread in body
• Bird
Diagnosis: • Direct fungal ... especially the CNS ... MC: CNS CSF: • ... arthroconidia; the fungus ... #Diagnosis #Management
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
Thromboembolism (7%) • CNS ... + Bleeding Treatment ... diagnosis #causes #treatment ... #management #hematology