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neurology differential erythematosus management sle systemic signs syndrome autoimmune cauda caudaequina cerebritis complications equina manifestations msk musculoskeletal myositis neuromyelitis nmo
Systemic Lupus Erythematosus (SLE): Musculoskeletal Manifestations • Immune Complex Deposition - Arthralgia, Arthritis
Normal CK - Myositis ... femoral heads • Myopathy ... (Also caused by ... pathophysiology #signs #symptoms ... #diagnosis
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
CNS Manifestations ... Aseptic Meningitis, Myelopathy ... autoantibodies that will cause ... permeability Diagnosis ... #neurology #rheumatology
Neuromyelitis Optica (NMO) - Clinical Manifestations • Optic neuritis: Reduced visual acuity, ranging from mild to
• Transverse myelitis ... pain • Extra-CNS ... disorders (Systemic lupus ... Manifestations #diagnosis ... #neurology #symptoms
Transverse Myelitis Overview Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
that results in CNS ... the spinal cord (Myelopathy ... bouts of HTN Diagnostic ... Bilateral signs and/or symptoms ... Diagnosis: •
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Differential Diagnosis ... and CNS • Headache ... • Transverse Myelitis ... : • Symptoms limited ... #Rheumatology
Cauda Equina Syndrome Overview Cauda Equina Syndrome: • Prevalence: 1:33,000-100,000 ppl/yr • Incidence: 1.5-3.4 million ppl/yr •
spine L1-L5 Symptoms ... equina syndrome (CES ... - Emergency Causes ... • Transverse myelitis ... #causes #neurology
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
Hypocomplementemia • Can cause ... demyelinating disease, myelopathy ... neuropathy, transverse myelitis ... • 8%-27% for CNS ... Sjogrens #Syndrome #Rheumatology
Autoimmune Myositis - Differential Diagnosis Framework Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
- Differential Diagnosis ... RP-ILD), dermato-rheumatologic ... nucleotidase 1A (Anti cN ... statins - probably caused ... #Myopathy #rheumatology
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