50 results
Weakness - Differential Diagnosis Framework

Approach To Weakness:
 • Non-neuromuscular disorder (Cardiac, pulmonary etc)
 • CNS ->
Diagnosis Framework ... pulmonary etc) • CNS ... • Acute stroke syndromes ... Paraneoplastic syndrome ... #Differential #Diagnosis
Neuromyelitis Optica (NMO) - Clinical Manifestations
 • Optic neuritis: Reduced visual acuity, ranging from mild to
Optica (NMO) - Clinical ... • Transverse myelitis ... pain • Extra-CNS ... Manifestations #diagnosis ... #neurology #symptoms
Autoimmune Myositis
Necrotizing myopathy is associated with higher CK levels, greater level of muscle weakness, less systemic
level of muscle weakness ... less systemic symptoms ... anti-synthetase syndrome ... /full triad at diagnosis ... have significant weakness
Hypothyroidism – symptoms and signs.

Symptoms: 
Tiredness/malaise, 
Weight gain,
Anorexia,
Cold intolerance, 
Poor memory,
Change in appearance, 
Depression, 
Poor libido,
Hypothyroidism – symptoms ... Symptoms: Tiredness ... Myalgia, Muscle weakness ... Carpal timel syndrome ... #Diagnosis #PhysicalExam
Causes of Neuromuscular Weakness
 • Spinal Cord: Demyelinating Disease (MS), Epidural abscess, Infarction, Syringomyelia, Tetanus, Transverse
Neuromuscular Weakness ... Tetanus, Transverse Myelitis ... Guillain-Barre syndrome ... heavy metals), Critical ... #differential #diagnosis
Myositis Specific Antibodies (MSAs)

Dermatomyositis: MDA5, TIF1y, NXP2, Mi-2, SAE
Anti-Synthetase Syndrome: Jo-1, PL7, PL12, EJ, OJ
Immune Mediated
Myositis Specific ... Anti-Synthetase Syndrome ... Antibodies #MSAs #clinical ... #diagnosis #rheumatology ... #table
Transverse Myelitis Overview

Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
that results in CNS ... - Clinical Presentation ... Weakness: - Weakness ... Bilateral signs and/or symptoms ... Diagnosis: •
Statin Induced Muscle Toxicity - Summary

Clinical Presentation:
 • Elevations of serum creatine kinase with proximal myalgia
Toxicity - Summary Clinical ... proximal myalgia and weakness ... symmetric muscle weakness ... Atorvastatin Diagnosis ... IU/I • SAMS clinical
Clinical Manifestations of Serotonin Syndrome
 • Ophthalmologic: Mydriasis, Ocular clonus (slow horizontal movements)
 • Gastrointestinal: Diarrhea,
Clinical Manifestations ... of Serotonin Syndrome ... Diaphresis, flushing • CNS ... #Symptoms #spectrum ... #signs #diagnosis
Spinal Cord Disorders - Differential Diagnosis Framework

Spinal cord neurological lesion:
Clinical findings:
 • Symptoms and signs below
- Differential Diagnosis ... neurological lesion: Clinical ... - Transverse myelitis ... MCTD, Sjogren syndrome ... spinalcord #disorders #diagnosis