29 results
differential systemic signs symptoms neurology erythematosus lupus sle autoantibodies causes management myopathies myopathy sclerosis antibodies autoimmune clinical comparison inflammatory msk
Myositis Specific Antibodies (MSAs) Dermatomyositis: MDA5, TIF1y, NXP2, Mi-2, SAE Anti-Synthetase Syndrome: Jo-1, PL7, PL12, EJ, OJ Immune Mediated
Myositis Specific ... Inclusion Body Myositis ... MithuRheum #Myositis ... #rheumatology # ... table
Autoimmune Myositis Necrotizing myopathy is associated with higher CK levels, greater level of muscle weakness, less systemic
Autoimmune Myositis ... triad of ILD, myositis ... /full triad at diagnosis ... #Autoimmune #Myositis ... #diagnosis #rheumatology
Myositis and Myopathies Polymyositis • Progressive, symmetric muscle weakness • Elevated CK, +Anti-Jo, +Anti-Mi2 Dermatomyositis
Myositis and Myopathies ... Inclusion Body Myositis ... , +Anti-dsDNA, Myositis ... BostonChiefs #Myositis ... #differential #diagnosis
Neuromyelitis Optica (NMO) - Clinical Manifestations • Optic neuritis: Reduced visual acuity, ranging from mild to
• Transverse myelitis ... pain • Extra-CNS ... positive NMO only): Myositis ... Manifestations #diagnosis
Weakness - Differential Diagnosis Framework Approach To Weakness: • Non-neuromuscular disorder (Cardiac, pulmonary etc) • CNS ->
Inclusion body myositis ... Pyomyositis, Lyme myositis ... Malignancy-associated myositis ... anti-RNP - (Myositis ... inclusion body myositis
Inflammatory Myopathies Dermatomyositis • Onset: Subacute • Pattern: Proximal • CK: Up to 50X ULN • Autoantibodies:
Necrotizing Autoimmune Myositis ... Inclusion Body Myositis ... #differential #diagnosis ... #comparison #rheumatology ... #table
Systemic Sclerosis (Scleroderma) Limited - CREST: • Calcinosis • Raynaud phenomenon • Esophageal dysmotility • Sclerodactyly •
involve DIP • Myositis ... #Scleroderma #diagnosis ... signs #symptoms #rheumatology
Autoantibodies in Rheumatology • Lupus (SLE): ANA (anti-nuclear antibody), dsDNA (double-stranded DNA), Anti-Smith, Anti-Ro (SSA) and
Autoantibodies in Rheumatology ... Peptide (CCP) • Myositis ... Autoantibodies #Rheumatology ... #diagnosis #associations ... #table
Transverse Myelitis Overview Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
Transverse Myelitis ... of Transverse Myelitis ... that results in CNS ... Transverse Myelitis ... /near level of myelitis
Systemic Sclerosis Associated Autoantibodies Anti-topoisomerase I (anti-Sc170): Diffuse skin disease, Pulmonary fibrosis Anti-centromere: Limited skin disease (~93-95%), Pulmonary
Anti-PM-Sc1: Overlap myositis ... Autoantibodies #diagnosis ... #rheumatology
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