31 results
Autoantibodies in Rheumatology
 • Lupus (SLE): ANA (anti-nuclear antibody), dsDNA (double-stranded DNA), Anti-Smith, Anti-Ro (SSA) and
Autoantibodies in Rheumatology ... Peptide (CCP) • Myositis ... Autoantibodies #Rheumatology ... #diagnosis #associations ... #table
Myositis Specific Antibodies (MSAs)

Dermatomyositis: MDA5, TIF1y, NXP2, Mi-2, SAE
Anti-Synthetase Syndrome: Jo-1, PL7, PL12, EJ, OJ
Immune Mediated
Myositis Specific ... Inclusion Body Myositis ... MSAs #clinical #diagnosis ... #rheumatology # ... table
Neuromyelitis Optica (NMO) - Clinical Manifestations
 • Optic neuritis: Reduced visual acuity, ranging from mild to
• Transverse myelitis ... pain • Extra-CNS ... positive NMO only): Myositis ... Manifestations #diagnosis ... #neurology #symptoms
Weakness - Differential Diagnosis Framework

Approach To Weakness:
 • Non-neuromuscular disorder (Cardiac, pulmonary etc)
 • CNS ->
- Differential Diagnosis ... pulmonary etc) • CNS ... -> PNS -> NMJ - ... #Differential #Diagnosis ... #neurology
Connective tissue disease-associated interstitial lung diseases

LIP: lymphoid interstitial pneumonia. NSIP: nonspecific interstitial pneumonia. OP: organizing pneumonia.
LungDisease #CTILD #Diagnosis ... Differential #Comparison #Table ... #Pulmonary #Rheumatology ... #Associations
Autoantibodies and their Disease Associations
ANA - Non-specific; common in SLE, autoimmune hepatitis
Anti-CCP, Rheumatoid factor - RA
Anti-dsDNA
their Disease Associations ... Autoantibodies #Associations ... #diseases #diagnosis ... #table #rheumatology
Argyll Robertson Pupil
Definition:
 - Irregular and small (1-2mm) pupil
 - Light-near dissociation (accommodation remains intact)
 -
and classical association ... Robertson #Pupil #neurology ... #diagnosis #ophthalmology ... #physicalexam
Inflammatory Myopathies
Dermatomyositis
 • Onset: Subacute
 • Pattern: Proximal
 • CK: Up to 50X ULN
 • Autoantibodies:
Associated Features: Diagnosis ... over years, often diagnosed ... #differential #diagnosis ... #comparison #rheumatology ... #table
What are common stroke mimics?
From Konrad CN, Crocco T, Biola J, Larrabee H. Is it stroke,
From Konrad CN, ... #Diagnosis #Differential ... Stroke #Mimics #Table ... #Misdiagnosed #Neurology
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
CNS Manifestations ... permeability Diagnosis ... Erythematosus #SLE #CNS ... #neurology #rheumatology ... #cerebritis #diagnosis