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differential management erythematosus lupus autoantibodies disease signs sle symptoms syndrome treatment ana antinuclear arthritis autoimmune behcet cerebritis comparison connectivetissuediseases ctild
Autoantibodies in Rheumatology • Lupus (SLE): ANA (anti-nuclear antibody), dsDNA (double-stranded DNA), Anti-Smith, Anti-Ro (SSA) and
Autoantibodies in Rheumatology ... Peptide (CCP) • Myositis ... • Scleroderma (Systemic ... #diagnosis #associations ... #table
Connective tissue disease-associated interstitial lung diseases LIP: lymphoid interstitial pneumonia. NSIP: nonspecific interstitial pneumonia. OP: organizing pneumonia.
SSc: systemic sclerosis ... LungDisease #CTILD #Diagnosis ... Differential #Comparison #Table ... #Pulmonary #Rheumatology ... #Associations
Neuromyelitis Optica (NMO) - Clinical Manifestations • Optic neuritis: Reduced visual acuity, ranging from mild to
• Transverse myelitis ... pain • Extra-CNS ... autoimmune disorders (Systemic ... Manifestations #diagnosis ... #neurology #symptoms
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
CNS Manifestations ... of Systemic Lupus ... permeability Diagnosis ... Erythematosus #SLE #CNS ... #neurology #rheumatology
Weakness - Differential Diagnosis Framework Approach To Weakness: • Non-neuromuscular disorder (Cardiac, pulmonary etc) • CNS ->
- Differential Diagnosis ... central nervous system ... Peripheral Nervous System ... #Differential #Diagnosis ... #neurology
Antinuclear antibodies and Systemic lupus Anti-dsDNA 60-80% Association with disease activity (when with Farr assay) and lupus nephritis. Can
antibodies and Systemic ... autoantibodies #Systemic ... erythematosus #diagnosis ... #rheumatology # ... table #ANA
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
et diutinum Neurologic ... neuropathy) • Systemic ... Scleromyxedema (CNS ... Paraproteinemias #Hematology ... #Differential #Diagnosis
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
Behçet's Syndrome Systemic ... Asia • HLA-B51 association ... skin injury) • Neurologic ... basal ganglia, CNS ... signs #symptoms #rheumatology
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
Parotid swelling CNS ... (CNS): demyelinating ... neuropathy, transverse myelitis ... • 8%-27% for CNS ... Sjogrens #Syndrome #Rheumatology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Differential Diagnosis ... Non-autoimmune rheumatologic ... and CNS • Headache ... • Transverse Myelitis ... #Rheumatology
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