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differential rheumatology autoantibodies comparison causes diseases management pulmonary adies altered ams ana antibodies antinuclear autoimmune behcet connectivetissuediseases ctild cushings disease
Autoantibodies and their Disease Associations ANA - Non-specific; common in SLE, autoimmune hepatitis Anti-CCP, Rheumatoid factor - RA Anti-dsDNA
their Disease Associations ... Anti-Scl-70 - Scleroderma ... Autoantibodies #Associations ... #diseases #diagnosis ... #table #rheumatology
Autoantibodies in Rheumatology • Lupus (SLE): ANA (anti-nuclear antibody), dsDNA (double-stranded DNA), Anti-Smith, Anti-Ro (SSA) and
LAC) • Sjogren Syndrome ... TIF1y, MDA5 • Scleroderma ... #Rheumatology #diagnosis ... #associations # ... table
Hypertension and Altered Mental Status (AMS) - Differential Diagnosis Framework Hypertension: • Hypertensive emergency • Hypertensive encephalopathy
- Differential Diagnosis ... • Cushing’s syndrome ... Hyperthyroidism CNS ... /agitation • CNS ... Polyarteritis nodosa • Scleroderma
Connective tissue disease-associated interstitial lung diseases LIP: lymphoid interstitial pneumonia. NSIP: nonspecific interstitial pneumonia. OP: organizing pneumonia.
PSS: Sjogren syndrome ... LungDisease #CTILD #Diagnosis ... Differential #Comparison #Table ... #Rheumatology #Associations
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
Asia • HLA-B51 association ... basal ganglia, CNS ... meningitis), MCC CNS ... ) Differential Diagnosis ... collaboration • CNS
Hyponatremia - Differential Diagnosis by Mechanism Decr Blood Pressure (“Decr Effective Circulating Volume”) - Volume depletion
- Differential Diagnosis ... - Cirrhosis Syndrome ... the lung) - CNS ... #Differential #Diagnosis ... #Table #Causes
Cushing Syndrome - Likelihood Ratios of Physical Exam Findings Moon facies LR +1.6 Central obesity LR +3.0 Generalized obesity
Cushing Syndrome ... , in women LR +NS ... SatyaPatelMD #Cushings #Syndrome ... #Ratios #LRs #PhysicalExam ... #diagnosis #endocrinology
Antinuclear antibodies and Systemic lupus Anti-dsDNA 60-80% Association with disease activity (when with Farr assay) and lupus nephritis. Can
Anti-dsDNA 60-80% Association ... SLE-SSc-AlM overlap syndromes ... Negative association ... erythematosus #diagnosis ... #rheumatology #table
Approach to Eosinophilic Lung Diseases • Acute Eosinophilic Pneumonia (< 1 wk) - ~30yo, M; Recent
Hypereosinophilic Syndrome ... , wt loss; CV, CNS ... #differential #diagnosis ... #comparison #table
Adie's Pupil What? Unknown nature & benign • Regular and mildly dilated pupil (4-6mm); • Light-near dissociaton;
Holmes-Adie Syndrome ... females Differential Diagnosis ... : • CN Ill Palsy ... #Adies #Pupil #PhysicalExam
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