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differential management rheumatology neurology autoantibodies diseases signs causes disease erythematosus hematology hypertension lupus ophthalmology symptoms systemic treatment video workup abnormal
Hypertension and Altered Mental Status (AMS) - Differential Diagnosis Framework Hypertension: • Hypertensive emergency • Hypertensive encephalopathy
Mental Status (AMS ... - Differential Diagnosis ... • Cushing’s syndrome ... /agitation • CNS ... Polyarteritis nodosa • Scleroderma
Autoantibodies and their Disease Associations ANA - Non-specific; common in SLE, autoimmune hepatitis Anti-CCP, Rheumatoid factor - RA Anti-dsDNA
their Disease Associations ... Anti-mitochondrial (AMA ... Anti-Scl-70 - Scleroderma ... #diseases #diagnosis ... #table #rheumatology
Autoantibodies in Rheumatology • Lupus (SLE): ANA (anti-nuclear antibody), dsDNA (double-stranded DNA), Anti-Smith, Anti-Ro (SSA) and
LAC) • Sjogren Syndrome ... TIF1y, MDA5 • Scleroderma ... #Rheumatology #diagnosis ... #associations # ... table
Patterns of Diseases on MRI FLAIR - Differential Diagnosis ADEM, Adreno-leukodystrophy, CADASIL, CNS, Lymphoma, High-Grade Glioma, HIV
- Differential Diagnosis ... Adreno-leukodystrophy, CADASIL, CNS ... Disease, Susac Syndrome ... #Differential #Diagnosis ... neuroradiology #clinical
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
Asia • HLA-B51 association ... • M > F Clinical ... basal ganglia, CNS ... (Clinical Dx). ... Reactive Arthritis, AS
BEE Syndromes - Non-inflammatory Causes Immune-mediated conditions affecting the Brain, Eye, and Ear Visual or auditory symptoms in
nervous system (CNS ... is important, as ... early diagnosis ... MRI lesions and clinical ... #differential #diagnosis
Antinuclear antibodies and Systemic lupus Anti-dsDNA 60-80% Association with disease activity (when with Farr assay) and lupus nephritis. Can
Anti-dsDNA 60-80% Association ... -15% If SLE is clinically ... SLE-SSc-AlM overlap syndromes ... erythematosus #diagnosis ... #rheumatology #table
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
CNS Manifestations ... Erythematosus (SLE) Clinical ... Demyelinating Syndrome ... permeability Diagnosis ... (for secondary APS
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
Macrophage Activation Syndrome ... Clinical Presentation ... Fever is the main clinical ... nervous system (CNS ... #Diagnosis #Management
Inherited Non-hemolytic Disorders of Hyperbilirubinemia == Disorders of Conjugation == Gilbert Syndrome: • 5-10% of the population
manifest only as ... jaundice on clinical ... symptoms, such as ... : • Type I CN ... bilirubin #hepatology #diagnosis
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