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rheumatology differential ana antinuclear management autoantibodies comparison diseases pulmonary causes clinical disease erythematosus lupus myositis patterns renal systemic adies agglutinin
Autoantibodies and their Disease Associations ANA - Non-specific; common in SLE, autoimmune hepatitis Anti-CCP, Rheumatoid factor - RA Anti-dsDNA
their Disease Associations ... Anti-Scl-70 - Scleroderma ... #diseases #diagnosis ... #table #rheumatology ... #antibodies
Autoantibodies in Rheumatology • Lupus (SLE): ANA (anti-nuclear antibody), dsDNA (double-stranded DNA), Anti-Smith, Anti-Ro (SSA) and
others (RNP, aPL antibodies ... TIF1y, MDA5 • Scleroderma ... #Rheumatology #diagnosis ... #associations # ... table
ANA Patterns and Associated Rheumatic Diseases: • Homogeneous: Systemic lupus erythematosus (SLE), Mixed connective tissue disease
SLE), Sjogren's Syndrome ... systemic sclerosis/scleroderma ... systemic sclerosis/scleroderma ... #Antinuclear #Antibodies ... #rheumatology #diagnosis
Hypertension and Altered Mental Status (AMS) - Differential Diagnosis Framework Hypertension: • Hypertensive emergency • Hypertensive encephalopathy
- Differential Diagnosis ... • Cushing’s syndrome ... Hyperthyroidism CNS ... /agitation • CNS ... Polyarteritis nodosa • Scleroderma
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
Antinuclear Antibodies ... Antibody refers to antibodies ... SLE), Sjogren's Syndrome ... Arthritis, Sjögren Syndrome ... #rheumatology #diagnosis
Myositis Specific Antibodies (MSAs) Dermatomyositis: MDA5, TIF1y, NXP2, Mi-2, SAE Anti-Synthetase Syndrome: Jo-1, PL7, PL12, EJ, OJ Immune Mediated
Myositis Specific Antibodies ... Anti-Synthetase Syndrome ... Myositis #Specific #Antibodies ... MSAs #clinical #diagnosis ... #rheumatology #table
Antinuclear antibodies and Systemic lupus Anti-dsDNA 60-80% Association with disease activity (when with Farr assay) and lupus nephritis. Can
Antinuclear antibodies ... Anti-dsDNA 60-80% Association ... SLE-SSc-AlM overlap syndromes ... erythematosus #diagnosis ... #rheumatology #table
ANA (Antinuclear Antibody) and ANCA (Antineutrophil cytoplasmic antibodies) • Systemic lupus erythematosus 1. Anti-dsDNA
Antineutrophil cytoplasmic antibodies ... Systemic sclerosis (scleroderma ... cases • Sjögren syndrome ... Antineutrophil #antibodies ... #diagnosis #rheumatology
Connective tissue disease-associated interstitial lung diseases LIP: lymphoid interstitial pneumonia. NSIP: nonspecific interstitial pneumonia. OP: organizing pneumonia.
PSS: Sjogren syndrome ... LungDisease #CTILD #Diagnosis ... Differential #Comparison #Table ... #Rheumatology #Associations
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
Asia • HLA-B51 association ... basal ganglia, CNS ... meningitis), MCC CNS ... ) Differential Diagnosis ... collaboration • CNS
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