36 results
ANA Patterns and Associated Rheumatic Diseases:
 • Homogeneous: Systemic lupus erythematosus (SLE), Mixed connective tissue disease
SLE), Sjogren's Syndrome ... systemic sclerosis/scleroderma ... systemic sclerosis/scleroderma ... ANA #patterns #rheumatology ... #diagnosis #differential
Scleroderma Mimics
 • Scleredema
 • Scleromyxedema (papular mucinosis)
 • Eosinophilic Fasciitis
 • Nephrogenic Systemic Fibrosis
 •
Scleroderma Mimics ... • Scleredema ... Fibrosis • POEMS Syndrome ... #Mimics #rheumatology ... #differential #diagnosis
Autoantibodies in Rheumatology
 • Lupus (SLE): ANA (anti-nuclear antibody), dsDNA (double-stranded DNA), Anti-Smith, Anti-Ro (SSA) and
Autoantibodies in Rheumatology ... LAC) • Sjogren Syndrome ... TIF1y, MDA5 • Scleroderma ... #diagnosis #associations ... #table
Hypertension and Altered Mental Status (AMS) - Differential Diagnosis Framework

Hypertension:
 • Hypertensive emergency
 • Hypertensive encephalopathy
- Differential Diagnosis ... • Cushing’s syndrome ... Hyperthyroidism CNS ... /agitation • CNS ... Polyarteritis nodosa • Scleroderma
Autoantibodies and their Disease Associations
ANA - Non-specific; common in SLE, autoimmune hepatitis
Anti-CCP, Rheumatoid factor - RA
Anti-dsDNA
Anti-Scl-70 - Scleroderma ... La) - Sjogren's syndrome ... Goodpasture's syndrome ... Associations #diseases #diagnosis ... #table #rheumatology
Differential diagnosis of schistocytes / fragmentation hemolysis:
 • Thrombotic microangiopathies (TMA)
    - TTP
Differential diagnosis ... hemolytic-uremic syndrome ... hypertension • Scleroderma ... #differential #diagnosis ... #hematology #hemolysis
Causes of Pericardial Effusion - Differential Diagnosis
Infectious:
 • Viral: Enterovirus, Herpesvirus, Adenovirus, Parvovirus
 • Bacterial: Mycobacterium
- Differential Diagnosis ... Non-Infectious: • Rheumatologic ... , Scleroderma, MCTD ... Disease, Behcet Syndrome ... #Differential #Diagnosis
Skin Conditions Associated with Joint Pain

Rash
	• Human parvovirus B19 infection

Malar rash
	• SLE
	• Human parvovirus B19 infection
	•
Telangiectasia • Scleroderma ... Thickened skin • Scleroderma ... Antiphospholipid-antibody syndrome ... #differential #diagnosis ... #rheumatology
Classification of Vasculitis 
Vasculitis of large vessels 
 - Arteritis temporalis (giant-cell arteritis) 
 - Takayasu
Churg-Strauss syndrome ... diseases - scleroderma ... Vasculitis #Vessels #Diagnosis ... #Rheumatology # ... Diagnosis
Antinuclear Antibodies (ANA)
ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
SLE), Sjogren's Syndrome ... systemic sclerosis/scleroderma ... Arthritis, Sjögren Syndrome ... ANA #patterns #rheumatology ... #diagnosis #differential