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diagnosis anemia cold dermatology extravascular hemolysis intravascular agglutinin aiha autoimmune burns cardiology chf chronic classification clinical compared criticalcare disease dyspnea
Autoimmune Hemolytic Anemia (AIHA) - Differential Diagnosis Table Warm AIHA (48-70%) Cold AHA (16-32%) • Donath-Landsteiner HA (paroxysmal
Autoimmune Hemolytic ... AIHA (48-70%) Cold ... HA (paroxysmal cold ... hemoglobinuria) • Cold ... #hematology
Causes of Extravascular and Intravascular Hemolysis - Differential Diagnosis Algorithm Extravascular - Spleen and RES-mediated hemolysis -
Causes of Extravascular ... - Differential ... Warm AIHA • Cold ... Complement-Mediated • Cold ... #Causes #Hematology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Extravascular Causes ... Autoimmune (AIHA)"Cold ... (e.g. primary cold ... #differential # ... diagnosis #hematology
Reflex Testing - Causes of Hyporeflexia and Hyperreflexia Focal Hyporeflexia: • Radiculopathy, Mononeuropathy, Polyneuropathy, Acute stroke,
Reflex Testing - ... , Acute spinal cord ... finding in spinal cord ... #Causes #differential ... #diagnosis #table
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
Cold Agglutinin ... Cold Agglutinins ... Positive Coombs testing ... younger pts) Differential ... #anemia #hematology
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
- Differential ... Diagnosis Algorithm ... Agglutination - Cold ... #workup #hematology ... #testing
Differential Diagnosis for Hemolytic Anemia Intrinsic Causes: • Enzyme deficiencies ex. G6PD, pyruvate kinase • Hemoglobinopathies
Differential Diagnosis ... for Hemolytic Anemia ... • AIHA: warm, cold ... #Anemia #Differential ... classification #hematology
Causes of Chronic Dyspnea - Differential Diagnosis Algorithm Pericardial • Effusion • Cardiac Tamponade* • Constriction Myocardial •
Causes of Chronic ... Dyspnea - Differential ... Diagnosis Algorithm ... • Asthma • COPD ... Pneumonia • ARDS • COPD
Causes of Pulmonary Hypertension - Differential Diagnosis Algorithm Pulmonary Arterial Hypertension • Idiopathic • Associated with:
Causes of Pulmonary ... Diagnosis Algorithm ... Hypoxemia: • COPD ... Miscellaneous: • Hematologic ... #Causes
Cold Urticaria Prevalence - 0.05% in the population Disease onset - Mostly 2nd to 4th decades of life Causes
Cold Urticaria Prevalence ... decades of life Causes ... skin contact with cold ... minutes after the cold ... #comparison #table
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