11 results
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
rapid onset of symptoms ... chronic onset of symptoms ... Symptoms: • Malaise ... -> AML: Blast crises ... Leukemia #Hematology #Oncology
Low Alkaline Phosphatase - Hypophosphatasia 

Is Low Alkaline Phosphatase Of Clinical Importance?

ALP enzyme- Discovered in 1923
Low
Most cases diagnosed ... membrane into the CNS ... collection with EDTA Pathophysiology ... mineralization Symptoms ... Phosphatase: • Other causes
Refeeding Syndrome: Pathogenesis and clinical findings

Patients at Risk of Refeeding Syndrome:
 - Little or no nutritional
PO4 -> decr RBC ATP ... - anemia - CNS ... Constipation - MSK ... Syndrome #diagnosis #pathophysiology ... #symptoms #signs
Fatigue and IBD Algorithm
 • 40-50% patients have fatigue despite clinical remission
 • Risk factors: BMI,
Fatigue and IBD Algorithm ... & Fe Sucrose > alt ... diet/deficiency symptoms ... and/or stress • Pts ... /other causes
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm
Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
Differential Diagnosis Algorithm ... lymphocyte predominant (LP ... pattern of spread, B symptoms ... Amy Chung, MD, MSc ... Classification #pathophysiology
UCSF COVID-19 Adult Clinical Evaluation Guide - Updated April 10 2020

Clinical Presentation
• Fever: hospitalized pts but
: hospitalized pts ... 30%; can be only symptom ... Cardiac: multiple case ... in <35% • AST/ALT ... Guide #Diagnosis #Algorithm
Transverse Myelitis Overview

Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
10-33% develop MS ... monophasic Pathophysiology ... that results in CNS ... Bilateral signs and/or symptoms ... • Infectious causes
Hodgkin's Lymphoma Overview

Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
accounts for 10% of all ... of about three cases ... ingestion • B symptoms ... Lymphoma (90-95% of cases ... classification #hematology #oncology
Summary of Oncologic Emergencies

Neutropenic fever:
- Fever + ANC < 500 → start cefepime ± vancomycin (if
Summary of Oncologic ... Treat underlying cause ... tocilizumab; call oncology ... AML (~20 %) and APL ... #Emergencies #Oncology
PFAPA Syndrome - Periodic Fever, Aphthous Stomatitis, Pharyngitis, and Adenitis

EPIDEMIOLOGY:
PFAPA is the most common syndrome entailing
fever (FMF) PATHOPHYSIOLOGY ... : The exact cause ... this disorder; its ... It causes the absolute ... known pathogenic cause