28 results
Causes of Thrombocytosis - Differential Diagnosis Algorithm
Spurious:
 • Artifact (redo CBC)
Autonomous:
 • Essential thrombocytosis
 • Polycythemia
Chronic Myelogenous Leukemia ... disorders • Celiac disease ... Damage: • Post-op surgery ... Non malignant hematologic ... effect following treatment
Pancytopenia - Differential Diagnosis

Congenital Diseases:
• GATA2 deficiency
• Fanconi’s anemia
• Wiskott-Aldrich syndrome
• Ribosomopathy or telomeropathy

Cancer:
• Leukemia
• Lymphoma

Inflammatory
Congenital Diseases ... Wiskott-Aldrich syndrome ... Cancer: • Leukemia ... : • Systemic lupus ... Differential #Diagnosis #Hematology
BEE Syndromes - Immune-mediated conditions affecting the brain, eye, and ear

Visual or auditory symptoms in conjunction
nervous system (CNS ... and less common diseases ... diagnosis and treatment ... • Systemic lupus ... polychondritis • Behcet disease
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Demyelinating Syndrome ... Cerebrovascular Disease ... Puncture, EEG Treatment ... #neurology #rheumatology ... diagnosis #management #treatment
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
extramedullary disease ... develop leukostasis syndrome ... : CNS manifestations ... • Tumor lysis syndrome ... #Hematology #Oncology
Systemic Lupus Erythematosus - Summary
Antinuclear (ANA) - 95% - Initial screening test
Anti-dsDNA - 50%
 • Associated
Systemic Lupus Erythematosus ... block • Sjogren syndrome ... polymyositis overlap syndrome ... Treatment: • ... #Systemic #Lupus
Causes of Fever of Unknown Origin (FUO) - Differential Diagnosis
 • Infection: Extrapulmonary tuberculosis, Abscess, Endocarditis,
Lemierre's syndrome ... Malignancy: - Hematologic ... malignancies: Lymphoma, Leukemia ... . autoimmune): Lupus ... , Kikuchi disease
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Malignancy (e.g. hematologic ... Shrinking lung syndrome ... involve PNS and CNS ... vein thrombosis Hematologic ... Hodgkin lymphoma and leukemia
Behcet's Syndrome - Treatment
Ulcers:
 • Treatment: Topical steroids
 • Prevention: Colchicine
 • Azathioprine for refractory disease
Arthritis:
Behcet's Syndrome ... : • Treatment: ... case by case) • Surgery ... #Syndrome #Treatment ... #pharmacology #rheumatology
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
• Systemic lupus ... nervous system (CNS ... SJIA], systemic lupus ... Treatment: • Corticosteroids ... Diagnosis #Management #Hematology