10 results
Hypereosinophilia and Hypereosinophilic Syndrome

 • Secondary Hypereosinophilic Syndrome
 • Clinically Relevant HES Variants
 • When to
Syndrome • Secondary ... Clinically Relevant HES ... Diagnosis and Treatment ... #Hematology #eosinophilia ... #eosinophils #diagnosis
Eosinophil Disorders Testing Algorithm
INDICATIONS FOR TESTING:
 • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
• Screen for secondary ... causes of eosinophilia ... (common causes ... glucocorticoid treatment ... Differential #diagnosis #hematology
Hypereosinophilia Syndrome (HES) - Diagnosis and Management
Definition: An absolute eosinophil count (AEC) greater than 1500 and
Hypereosinophilia Syndrome (HES ... Secondary Causes ... - Lymphocytic HES ... #eosinophilia # ... diagnosis #hematology
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
leakage of RBC's secondary ... Thrombocytopenia: ITP • Secondary ... : • DIC, TTP/HUS ... Differential #Diagnosis #hematology ... #rheumatology #
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
autoantibodies that will cause ... Puncture, EEG Treatment ... anticoagulants (for secondary ... APS), Secondary ... #neurology #rheumatology
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
+ Bleeding Treatment ... Treat primary cause ... Coagulation #diagnosis #causes ... #treatment #management ... #hematology
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
involvement • 30%: CNS ... -> AML: Blast crises ... • (Peripheral eosinophilia ... bone marrow and secondary ... #Leukemia #Hematology
Hemophagocytic Lymphohistiocytosis (HLH) Treatment
Primary HLH:
 - HLH-94 Protocol
    • Dexamethasone
Lymphohistiocytosis (HLH) Treatment ... (depending on CNS ... transplantation Secondary ... autoimmune disease, treatment ... #management #hematology
Sjogren's Syndrome Overview

Epidemiology:
• F > M: 9:1
• 5-6th Decades (can be any age)

Autoimmune exocrinopathy multisystemic disease
other diseases • Secondary ... Hypocomplementemia • Can cause ... Nephrogenic DI Hematologic ... Adenocarcinoma Treatment ... Sjogrens #Syndrome #Rheumatology
Hodgkin's Lymphoma Overview

Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
of about three cases ... persons • It has ... Lymphoma (90-95% of cases ... Hodgkin Lymphoma Treatment ... classification #hematology