19 results
CNS Infection in HIV / AIDS - Differential Diagnosis Framework

Principles of HIV-Associated CNS Opportunistic Infections:
 •
HIV / AIDS - Differential ... Principles of HIV-Associated ... encephalopathy #HIV ... #differential # ... opportunistic #InfectiousDiseases
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Purpura - Differential ... Splenomegaly - CTD ... • HCV, HBV Not ... Vasculopathy #Purpura #Differential ... #rheumatology #
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
Agglutinin Syndrome (CAS ... Mycoplasma, EBV, HIV ... disease (younger pts ... ) Differential ... hemolytic #anemia #hematology
Venous Thrombosis vs Arterial Thrombosis - Differential Diagnosis Framework

VENOUS THROMBOSIS

 • Acquired Risk Factors:
	- >48 hours
Arterial Thrombosis - Differential ... Hematological: - HIT ... Venous #Arterial #pathophysiology ... #hematology #differential
Paraproteinemias

Entities That Can Feature A Monoclonal Protein/M Component:
• MM
• WM
• MGUS
• MGCS
• MGRS
• Splenic Marginal Zone
Zone Lymphoma (HCV ... +GI+CVS+joints) ... • Amyloidosis (CVS ... Paraproteinemias #Hematology ... #Monoclonal #Differential
Lung Infections in HIV - Differential Diagnosis Framework

Disease by CD4 Count:
Any CD4 Count:
 • Mycobacterium tuberculosis,
- Differential ... • CT: Halo sign ... Lymphadenopathy, CNS ... AIDS #pulmonary #differential ... #diagnosis #infectiousdiseases
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
Vasculitides - Differential ... • ANA (Suggest CTD ... Cryoglobulins • HIV ... • HBV HCV • ... #diagnosis #rheumatology
Antinuclear Antibody Testing - Nuclear and Cytoplasmic Patterns
Nuclear Patterns:
 • Homogeneous pattern: 
   -
- SLE, SjS, CTD-ILD ... Rods/rings: - HCV ... Cytoplasmic #Patterns #differential ... #diagnosis #rheumatology
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
protein C and S Pathophysiology ... Thromboembolism (7%) • CNS ... deficiency) • HIT ... treatment #management #hematology
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
ATRA treatment Pathophysiology ... initiation • Differential ... • Steroids: IV ... diagnosis #management #hematology