4123 results
Inflammatory Cascade: Pathogenesis and Clinical Findings
Continued Innate Immunity
 • Phagocytosis: (main mechanism) neutrophils and macrophages engulf
perforin-mediated wall ... • Humoral: (B cell ... : (T cell response ... and cytotoxic cell ... #Inflammation #pathophysiology
Tumor lysis syndrome (TLS) - Pathophysiology:
→ Massive tumor cell lysis
→ Release of large amounts of K+,
syndrome (TLS) - Pathophysiology ... Massive tumor cell ... cytotoxic therapy of ALL ... syndrome #TLS #Pathophysiology
Causes and Pathophysiology of Hypertension

#Causes #Pathophysiology #Hypertension #Primary #Essential #Secondary #Differential

** GrepMed Recommended Text: Guyton and
Causes and Pathophysiology ... Hypertension #Causes #Pathophysiology ... Text: Guyton and Hall
Sickle Cell Vaso-Occlusive Crisis

#SickleCell #Crisis #Vasoocclusive #AcuteChestSyndrome #ACS #Pathophysiology #Hematology
Sickle Cell Vaso-Occlusive ... AcuteChestSyndrome #ACS #Pathophysiology
Gastric Acid Secretion - Pathophysiology
Chief cell - Pepsinogen
Parietal cell - Acid, Intrinsic factor
G cell - Gastrin
Inhibitors:
Acid Secretion - Pathophysiology ... Chief cell - Pepsinogen ... Parietal cell - ... Intrinsic factor G cell ... Acid #Secretion #Pathophysiology
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
Leukemias Overview: ALL ... CML, AML, APML, CLL ... age • 75% of ALL ... ALL Symptoms: ... ALL can present
The cardiac cycle and the ECG, all together explained

#Pathophysiology #Cardiology #CardiacCycle #Stages #Systole #Diastole #HeardSounds #Pressures
cycle and the ECG, all ... explained #Pathophysiology
Hypercalcemia of Malignancy - Pathophysiology
PTH-mediated
 • Parathyroid cancer
 • Ectopic production: Small cell lung cancer, ovarian
of Malignancy - Pathophysiology ... production: Small cell ... bone • Squamous Cell ... of lung, Renal Cell ... Hypercalcemia #Malignancy #Pathophysiology
Retinoblastoma: Pathogenesis and clinical findings
 • Sporadic mutation -> One allele of RB1 tumor suppressor gene
mutated in one cell ... transformation of the cell ... gene mutated in all ... transformation of the cell ... Retinoblastoma #pathophysiology
Blood Disorders - Markers and Differential Diagnosis Algorithm 
Acute
 • Myloid (AML) - CD13, CD33, CD34,
• Lymphoid (ALL ... Involvement - B-cell ... CD10 - T-cell ... • Lymphoid (CLL ... Cells - B-cell