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diagnosis infectiousdiseases differential infective negative treatment bcnie bloodcultures cardiology causes clinical infection antibiotics antifungal bacteria blastomycosis bloodculture bloodstream candidemia candidiasis
My Patient with Infective Endocarditis (IE) Has Negative Blood Cultures - Did they receive antibiotics prior
with Infective Endocarditis ... Fungal (Histoplasma ... patient a surgical candidate ... BloodCultures #Diagnosis #Management ... #Algorithm
Microorganisms Responsible for Infective Endocarditis Native valves: - Streptococcus viridans - Enterococci - Other streptococci
for Infective Endocarditis ... Gram-negative bacilli - Fungi ... (Candida, Aspergillus ... Histoplasma) - Culture ... streptococci - Culture
Causes of blood culture negative infective endocarditis Bartonella spp, Brucella spp, Coxiella burnetii, Chlamydia spp, Tropheryma whipplei,
Causes of blood culture ... negative infective endocarditis ... Tropheryma whipplei, Fungi ... (Aspergillus, Candida ... #negative #Endocarditis
Common Fungal Pathology • Candida - Small yeast intermingled with pseudohyphae • Aspergillosis - Septate
Common Fungal Pathology ... • Candida - Small ... Medicine @ucsdim #Fungal ... Pathology #clinical #microscopy ... #table #atlas #
Blood Culture Collection Algorithm - Adult Patients with Suspected Systemic Infection Pawlowicz et al evidenced based
Algorithm - Adult ... Algorithm Source ... Implementation-of-an-evidence-based-algorithm-reduces-blood-culture-overuse-in-an-adult-emergency-department.php ... tract infection, endocarditis ... #Management #BloodCultures
Flutycosine - Antibiotics Class Overview - Mechanism: 5-FC interferes with DNA and protein synthesis. Only
B for initial management ... several severe fungal ... meningitis, severe candidal ... infections (endocarditis ... for non-severe candida
Candidemia Workup and Management - IDSA Guidelines 1) Antibiotics • Empiric: Echinocandins (e.g. micafungin) for most patients
Candidemia Workup and Management ... Susceptibilities, Negative Cultures ... clinical concern for endocarditis ... #candida #candidiasis ... #treatment #fungal
Endocarditis Algorithm - Infective vs Noninfective Causes Noninfective: • Malignancy • Autoimmune disease • Systemic infection Native Valve
Endocarditis Algorithm ... • HACEK • Culture-negative ... Gram-negative bacilli • Fungi ... Gram-negative bacilli • Fungi ... #Algorithm #Infective
Blood Culture-Negative Infective Endocarditis (BCNIE) Definition: No etiology found after 3 separate blood cultures remain negative for
Infective Endocarditis ... fastidious bacteria or fungi ... Tropheryma whipplei, Fungi ... (Aspergillus, Candida ... Negative #Infective #Endocarditis
Endocarditis Summary Who? Infectious: • Pre-existing valvular disease • Prosthetic valve • Congenital heart disease • IV substance use • IV catheter • Recent
Hypercoagulable (APLAS ... 90% of IE cases Culture ... staphylococci Culture ... • Blood cultures ... #diagnosis #management
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