21 results
Fungal biomarkers
Beta-d-glucan
Aspergillus galactomannan

By Dr. Sara Dong @swinndong via Febrile [febrilepodcast.com]

#ID  #Infectious Diseases  #Infections
#Differential #Ddx
Fungal biomarkers ... Beta-d-glucan Aspergillus ... #Fungi #BDG #BDGlucan ... galactomannan #Aspergillus ... #Candida #Microbiology
Morphology and Descriptions of Fungal Infections with Hyphae or Pseudohyphae in Tissues
Yeasts with Pseudohyphae: 
 •
Consistent with Candida ... other hyaline fungi ... with dematiaceous fungi ... #fungi #infections ... septations #pathology #atlas
Microorganisms Responsible for Infective Endocarditis

Native valves:
 - Streptococcus viridans 
 - Enterococci 
 - Other streptococci
Gram-negative bacilli - Fungi ... (Candida, Aspergillus ... Histoplasma) - Culture ... Gram-negative bacilli - Fungi ... streptococci - Culture
Fungal Biomarkers: Comparing Beta-D-Glucan and Aspergillus Galactomannan
Beta-D-Glucan:
 • Polysaccharide cell wall component of many fungi
 •
Fungal Biomarkers ... component of many fungi ... • Pathogens: Candida ... , Aspergillus ... febrilepodcast #Fungal
Important Fungal Stains
Mycology Lab:
 • Calcofluor white - Fluorochrome that binds glucans and chitin in fungal
preparation from culture ... cell response to fungi ... doesn't stain most fungi ... exceptions are Aspergillus ... staining #diagnosis #fungi
Morphology and Descriptions of Endemic Fungal Infections with Yeasts in Tissues
Broad-based budding yeasts:
 • Description: Broad-based
Cryptococcus, and Aspergillus ... other hyaline fungi ... with dematiaceous fungi ... #fungi #infections ... morphology #pathology #atlas
Causes of Culture Negative Abscess - Differential Diagnosis Framework
Consider prior antibiotics as a cause of a
Causes of Culture ... of a negative culture ... : Aspergillus, Cryptococcus ... Scedosporium, endemic fungi ... Kumfer @AnnKumfer #Culture
Transplant Infections Timeline
Pre-transplant:
 • Common bacteria (endogenous): Staphylococci (skin), Gram-negative bacilli (gut)
 • Viruses: HSV (reactivation)
Engraftment:
difficile (gut) • Fungi ... : Candida spp. ... Adenovirus, RSV • Fungi ... : Aspergillus spp ... reactivation), RSV • Fungi
Causes of blood culture negative infective endocarditis

Bartonella spp, Brucella spp, Coxiella burnetii, Chlamydia spp, Tropheryma whipplei,
Causes of blood culture ... Tropheryma whipplei, Fungi ... (Aspergillus, Candida ... identified with modern culture ... diagnosis #causes #culture
Morphology and Descriptions of Endemic Fungal Infections with Yeasts in Tissues
Broad-based budding yeasts:
 • Description: Broad-based
Descriptions of Endemic Fungal ... Cryptococcus, and Aspergillus ... swinndong #endemic #fungal ... pathology #clinical #atlas ... #fungi #microbiology