845 results
Nephrotic Syndrome - Classification
 - Podocytopathies
 - Immunocomplex Deposits 
 - Other substances Deposits 

#Nephrotic #Syndrome
Immunocomplex Deposits ... Other substances Deposits
This image shows glomerular tuft with overall intact architecture. Discrete masses of specular amyloid interrupt smooth
arkanalabs #CapillaryLoop ... #desposition #deposits
Membranoproliferative Glomerulonephritis (MPGN) AKA: Mesangiocapillary GN
 • Active Urine Sediment (dysmorphic RBC, RBC casts, +/- proteinuria)
glomerulopathy (Dense deposit ... Minimal immune deposits
Type III Hypersensitivity: Pathogenesis and clinical findings
Definition: Small antigen-antibody complexes (produced from normal immune response to
foreign substances) deposit ... Allergy #Immunology #pathophysiology
Cutaneous Manifestations of Monoclonal Gammopathy
 • Extravascular lg Deposits: Systemic amyloidosis, Nodular amyloidosis, Macroglobulinoderma, Follicular hyperkeratotic
Extravascular lg Deposits ... Intravascular lg deposits
Rapidly Progressive Glomerulonephritis (RPGN) 
 - Loss of kidney function over a short period of tirne
Presence of immune deposits ... on IF • No EM deposits ... Minimal immune deposits
Monoclonal Gammopathy of Clinical Significance (MGUS) - Differential Diagnosis

Neurologic-Centered:
 (+) Systemic Features: POEMS, AL amyloid, Cryoglobulinemia
• Organized Ig deposits ... Non-organized Ig deposits ... monoclonal Ig deposits ... gammopathy • (-) Ig deposits
Diabetes Pathophysiology and Medication Targets

The ominous octet is one concept that summarizes the different pathophysiologic pathways
Diabetes Pathophysiology ... the different pathophysiologic ... #Diabetes #Pathophysiology
Hydroxyapatite Deposition Disease (HADD) - MSK Radiology
Imaging Findings:
 • Ovoid hypointense structures along the bursal surface
Hydroxyapatite deposits ... Hydroxyapatite deposits ... - Deposits ... Hydroxyapatite deposits
Diagnosis of IgA Vasculitis (Henoch-Schönlein Purpura) - French Vasculitis Study Group 

1) Suggestive clinical manifestations
dominant immune deposits ... - Dominant IgA deposits ... with vascular IgA deposits