14 results
Coagulation Cascade and Anticoagulant Sites of Action

- Amy Chung, MD, MSc https://twitter.com/AmyChung

#AntiCoagulation #Cascade #Anticoagulants #Medications #Pharmacology
Coagulation Cascade ... and Anticoagulant ... twitter.com/AmyChung #AntiCoagulation ... #Cascade #Anticoagulants ... #Medications #Pharmacology
Stroke and bleeding risk stratification with the CHADS2-VASc and HAS-BLED schemas

#Diagnosis #Hematology #CHADS2 #CHADS2VASc #HASBLED #Comparison
Stroke and bleeding ... CHADS2-VASc and HAS-BLED ... #Score #Risk #Stroke ... #Bleed #Anticoagulation ... #AFib
Coagulation Cascade - Anticoagulant Targets
Here's the brief overview of where the main anticoagulants work on the
- Anticoagulant ... where the main anticoagulants ... #Anticoagulant ... #Targets #Anticoagulation ... #Pharmacology
Coagulation Cascade - Actions of Anticoagulants
 • Heparin: Unfractionated heparin, Enoxaparin, Daltaparin
 • Fondaparinux
 • Direct
- Actions of Anticoagulants ... - Strong Medicine ... #Anticoagulants ... #anticoagulation ... #pharmacology
CHA2DS2VASc vs HAS-BLED scores for stroke risk and bleed risk on anticoagulation

C	Congestive Heart Failure	1

H	Hypertension	1

A2	Age >75	2

D	Diabetes Mellitus	1

S2	Stroke,
CHA2DS2VASc vs HAS-BLED ... risk and bleed ... risk on anticoagulation ... #Bleed #Anticoagulation ... #AFib #Diagnosis
Choice of anticoagulant for treatment of pulmonary embolism
 • Malignancy - LMWH
 • To avoid parenteral
Choice of anticoagulant ... history of Gl bleed ... Pregnancy - LMWH #anticoagulant ... decisionaid #vte #anticoagulation ... #pharmacology
Perioperative Management of DOACs
Problem:
 ✖ Each year approximately 250,000 patients on chronic anticoagulation in North America
patients on chronic anticoagulation ... direct acting oral anticoagulants ... to assess for anticoagulant ... Therapy • Low Bleed-Risk ... Management #Treatment #pharmacology
Antiplatelet Medications - Summary Table

Aspirin - Inhibits cyclooxygenase, preventing formation of thromboxane A2
 • Acute coronary
inhibitor and anticoagulation ... Alternative to anticoagulation ... in a-fib P2Y12 ... with aspirin and anticoagulation ... Summary #Table #Pharmacology
HAS-BLED Score for Major Bleeding Risk of Anticoagulation in Atrial Fibrillation

A clinical mnemonic to estimate the
HAS-BLED Score for ... Bleeding Risk of Anticoagulation ... point each) S - Stroke ... #Anticoagulation ... #AFib #BLEEDING
Beta Blockers - Pharmacology Comparison Table
Metoprolol:
 • Receptors: β1
 • Indications: Rate control of a-fib/a-flutter, Suppression
Beta Blockers - Pharmacology ... prophylaxis, Variceal bleed ... Eric Strong @DrEricStrong ... - Strong Medicine ... Beta #Blockers #Pharmacology