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diagnosis causes management algorithm differential insufficiency growthhormone pediatrics pituitary primary signs symptoms acromegaly addisons cah coagulation comparison congenitaladrenalhyperplasia dic disease
Feedback Loop: Growth Hormone (GH) Growth Hormone: • Liver -> GHR activates JAK-STAT pathway -> Incr IGF1
Growth Hormone (GH ... /Symptoms: • GH ... expansion (e.g. carpal ... #FeedbackLoop #endocrinology ... #pathophysiology
Growth Hormone Excess - Pathogenesis and clinical findings • Acromegaly and gigantism share the same pathophysiology
share the same pathophysiology ... GH excess prior ... overgrowth: • Carpal ... signs #symptoms #endocrinology ... #pathophysiology
Acromegaly - Diagnosis and Management Summary - GrepMed Handbook Clinical Presentation: • Classic Acromegaly: frontal
paresthesias (carpal ... malignancy Pathophysiology ... pseudo-acromegaly, obesity, hypothyroidism ... Diagnosis #Management #Endocrinology ... #Treatment #Pathophysiology
Primary vs Secondary Adrenal Insufficiency - Pathophysiology Primary AI = adrenal glands themselves are the problem. This
Insufficiency - Pathophysiology ... Primary AI = adrenal ... Secondary AI = the ... Insufficiency #Pathophysiology ... #endocrinology
Tall Stature - Differential Diagnosis Algorithm Normal Growth (BA=CA) • Familial Tall Stature • XYY Syndrome Obese BMI
Puberty Onset • GH ... Excess • Hyperthyroidism ... Precocious Puberty • Adrenal ... • Congenital Adrenal ... Diagnosis #Algorithm #endocrinology
Infographic depicting the main pearls of various types of congenital adrenal hyperplasia for the medical student.
of congenital adrenal ... diagnosis #comparison #treatment ... #Peds #Endocrinology ... #Adrenal #pathophysiology
Short Stature - Differential Diagnosis Algorithm Normal Variant, Normal Puberty Onset (BA = CA) • Familial Short
Cushing's Disease • GH ... Dwarfism) • Hypothyroidism ... • Congenital Adrenal ... Panhypopituitarism Treatment ... Diagnosis #Algorithm #endocrinology
Primary Adrenal Insufficiency Addison's Disease - Damage of the adrenal glands with lack of cortisol, androgens and
Primary Adrenal ... disorder - Primary hypothyroidism ... /dL -> Primary AI ... ug/dL Primary AI ... addisons #disease #endocrinology
Adrenal Insufficiency Treatment - Stress Dose Steroids • Large Bore IVs, ~2L IVF & Draw workup
Treatment - Stress ... before concurrent hypothyroidism ... Insufficiency #AI ... #Treatment #Management ... StressDose #Steroids #endocrinology
Rhabdomyolysis - Differential Diagnosis and Management Summary Trauma: • Immobilization, Crush iniury, Compartment syndrome, Electrical injury Exertional: •
Endocrine (Hypo/Hyperthyroidism ... Dermatomyositis) AKI - Pathophysiology ... renal ischemia ... oxidative iniury Treatment ... Summary #causes #treatment
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