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diagnosis management symptoms endocrinology orthopedics radiology sports wrist xray acromegaly anomalous cardiology causes complications dissociation excess feedbackloop fracture gait overproduction
Feedback Loop: Growth Hormone (GH) Growth Hormone: • Liver -> GHR activates JAK-STAT pathway -> Incr IGF1
Growth Hormone (GH ... activates lipolysis Signs ... expansion (e.g. carpal ... metabolic abn #GrowthHormone ... endocrinology #pathophysiology
Growth Hormone Excess - Pathogenesis and clinical findings • Acromegaly and gigantism share the same pathophysiology
share the same pathophysiology ... overgrowth: • Carpal ... fraction • HTN #GrowthHormone ... #diagnosis #signs ... endocrinology #pathophysiology
Acromegaly - Diagnosis and Management Summary - GrepMed Handbook Clinical Presentation: • Classic Acromegaly: frontal
and Management Summary ... paresthesias (carpal ... decade → peripheral/acral ... malignancy Pathophysiology ... Endocrinology #Treatment #Pathophysiology
Total Anomalous Pulmonary Venous Return (TAPVR) • Introduction • Classification • Pathophysiology of TAPVR • Presentation
Classification • Pathophysiology ... Classic “snowman sign ... Outcomes by Cara ... cardiology #peds #pediatrics ... #summary
Triquetral Fracture The triquetrum is the second most commonly fractured carpal bone. Look for the "pooping duck
commonly fractured carpal ... "pooping duck sign ... Here's a quick summary ... "pooping duck sign ... Orthopedics #Sports #MSK
Scapholunate Dissociation The spacing between all carpal bones should be 1-2 mm, look for the "Terry Thomas"
spacing between all carpal ... "Terry Thomas" sign ... Here's a quick summary ... ("Terry Thomas sign ... Orthopedics #Sports #MSK
Trendelenburg Gait: Pathogenesis and clinical findings Skeletal Pathology of the Hip • Arthritis • Congenital hip dysplasia
in the Spinal canal ... Trendelenburg #Gait #pathophysiology ... causes #symptoms #signs ... #diagnosis #msk
Scoliosis: Pathogenesis and clinical findings (Cobb Angle > 10 Degrees) • Incr Axial rotation of thoracic
intervertebral canal ... #Scoliosis #pathophysiology ... #msk #diagnosis ... #signs #symptoms
Sarcoidosis - Diagnosis and Management Summary Epidemiology 1) High incidence in Scandinavian countries (11-24 cases per 100,000 individuals
and Management Summary ... survival is 93-95% Pathophysiology ... anterior/posterior MSK ... Diagnosis #Management #Signs
Paget’s Disease: Complications Abnormal Osteoclasts cause excessive bone turnover -> Incr bone resorption, Incr (abnormal) bone formation MSK
bone formation MSK ... the vertebral canal ... PagetsDisease #pathophysiology ... #diagnosis #signs
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