25 results
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome ... Triggers: ATRA treatment ... : >3 symptoms, or ... sepsis), PE, DAH, CHF ... #oncology
Chronic Lymphocytic Leukemia (CLL) - Summary
Overview: 
 • Most common leukemia in adults
 • Disorder of
minimal tumor burden Diagnosis ... immunophenotype Clinical ... Lymphocytic #Leukemia #oncology ... #hematology #hemeonc ... #diagnosis #management
Krabbe Disease 

Check out this interesting case of Krabbe disease, a rare genetic leukodystrophy. Diagnosis was
Diagnosis was made ... testing and expedite treatment ... neurotoxic • Symptoms ... • Dec NAA, inc Cho ... Krabbe #Disease #Diagnosis
Summary of Oncologic Emergencies

Neutropenic fever:
- Fever + ANC < 500 → start cefepime ± vancomycin (if
Summary of Oncologic ... interventional radiology ... → no immediate treatment ... #Emergencies #Oncology ... #HemeOnc #Diagnosis
TRALI vs TACO - Transfusion Reactions
TRALI:
 • Epidemiology: 0.1% of transfused patientsl
 • Risk factors: Critical
Risk factors: Critical ... ARDS to explain symptoms ... : 33% • Treatment ... : Age>60, CKD, CHF ... #diagnosis #comparison
Sweet Syndrome

Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
development of skin symptoms ... Leukemia cutis Diagnosis ... Treatment: - Systemic ... #diagnosis #dermatology ... #oncology
Refeeding Syndrome Overview

What Is It?
	• Electrolyte/fluid shifts caused by initiation of nutrition in severely malnourished patient.
may cause severe clinical ... decompensation (CHF ... overload) Other Symptoms ... hyperparathyroidism Treatment ... #Differential #Diagnosis
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Aplastic Anemia Clinical ... aplastic anemia Treatment ... • Improve the symptoms ... Aplastic #Anemia #oncology ... #hematology #diagnosis
Posterior Reversible Encephalopathy Syndrome (PRES) Overview

Clinico-Radiological Syndrome, characterized by:
 • Headache
 • Seizures
 • Altered mental
brain PRES Clinical ... PRES-Associated Clinical ... Neurological symptoms ... epilepticus Treatment ... underlying cause • Treatment
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
Orange or Hep C Clinical ... with no early symptoms ... microglobulin Treatment ... #workup #oncology ... #hematology