31 results
Landolfi’s Sign on Physical Exam

A 73-year-old man presented with shortness of breath. On ocular exam, pupil
Landolfi’s Sign ... On ocular exam, ... present in this disease ... Clinical #Video #Ocular ... #Iris #AorticRegurgitation
Spondylolysis & Spondylolisthesis: Pathogenesis and Clinical Findings

Pars interarticularis stress fracture (spondylolysis) - most frequently in the
tenderness • Positive ... XR — scotty dog sign ... vertebrae • CT - collar ... pathophysiology #signs ... #symptoms
Whipple Disease (Tropheryma whipplei) - Diagnosis and Management 

Caused by: Tropheryma whipplei

Symptoms and Signs:
1. Migratory poly/oligoarthralgia
Whipple Disease ... Tropheryma whipplei Symptoms ... and Signs: 1. ... Oculomasticatory/oculo-facial-skeletal ... MatthewHoMD #Whipple #Disease
Stages of Syphilis
Early Primary:
 • Painless chancre
 • Regional lymphadenopathy
Early Secondary:
 • Fever, malaise
 • Rash
Early Latent: • Positive ... testing • No symptoms ... • Gummatous • Nodular ... Late Latent: • Positive ... #signs #diagnosis
Characteristic clinical manifestations of Down syndrome 
 
Typical craniofacial appearance 
 • Round face and flat
Brushfield spots in iris ... • Hirschsprung disease ... impairment from cataracts ... • Alzheimer's disease ... PhysicalExam #Features #Signs
Primary Biliary Cirrhosis - Diagnosis Algorithm
Symptoms: Fatigue, Pruritus, Right upper quadrant discomfort
Signs: Jaundice, Xanthelasmata, Hepatomegaly
Associated history:
Diagnosis Algorithm Symptoms ... quadrant discomfort Signs ... Associated history: Symptoms ... of autoimmune disease ... Positive AMA or
Blurry Vision - Differential Diagnosis Framework

Anatomical Approach to Eye Disease:
1. Lids/Lashes
2. Extraocular Muscles/Motility
3. Conjunctiva/Sclera
4. Cornea
5. Anterior
Approach to Eye Disease ... Iris 7. ... Ocular Adverse Effects ... Trauma Cornea/Iris ... Uveitis Lens: • Cataracts
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
ulceration • Ocular ... meningitis), MCC CNS symptoms ... Skin lesions • Positive ... diagnosis #management #signs ... #symptoms #rheumatology
Neuromyelitis Optica (NMO) - Clinical Manifestations
 • Optic neuritis: Reduced visual acuity, ranging from mild to
desaturation, Scotoma, Ocular ... mainly AQP4-lgG disease ... complications (AQP4-positive ... diagnosis #neurology #symptoms ... #signs
Immune Reconstitution Inflammatory Syndrome - Overview of IRIS

What Is IRIS?
	• A state of hyperinflammatory response that
worsening of that disease ... pericarditis, peritoneal disease ... skin lesions, ocular ... Zoster flare, ocular ... with severe symptoms