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diagnosis differential algorithm deficiency nutrition thrombocytosis bowel disease evaluation ferritin gastrointestinal ibs irritable mds myelodysplasia myelodysplastic oncology platelets syndrome syndromes
Causes of Thrombocytosis - Differential Diagnosis Algorithm Spurious: • Artifact (redo CBC) Autonomous: • Essential thrombocytosis • Polycythemia
Causes of Thrombocytosis ... Inflammatory: • IBD ... disorders • Celiac ... malignancy • Iron ... deficiency anemia
Suspected Celiac Disease - Diagnosis Algorithm Celiac disease suspected: • Signs and symptoms of celiac disease •
disease • Iron-deficiency ... anemia unresponsive ... without discernable cause ... Inflammatory (IBD ... Diagnosis #Algorithm #gastroenterology
Causes of Iron Deficiency • Diet: ↓ Intake, e.g. vegan, Malnutrition, Polyphenol / tannins, ↓ Vitamin
Causes of Iron Deficiency ... Drugs, H pylori, Celiac ... Inflammation: IBD ... #Deficiency #Causes ... differential #diagnosis #anemia
Iron Deficiency Anemia - Differential Diagnosis Algorithm Labs: Ferritin, iron, transferrin, TIBC, TSAT, sTfR • Blood loss:
Anemia - Differential ... - Structural: Celiac ... Tropical sprue, IBD ... #Deficiency #Anemia ... Algorithm #ferritin #hematology
Gastrointestinal Evaluation of Iron Deficiency Anemia In patients with anemia, diagnose iron deficiency if: • Ferritin <
Deficiency Anemia ... patients with anemia ... tests Test for celiac ... Gastrointestinal #Evaluation #workup ... #diagnosis #gastroenterology
Causes of Iron Deficiency • Inadequate Intake: Vegetarian/vegan diet, Malnutrition • Increased Body Needs: Infants/preschoolers, Pregnancy,
Causes of Iron Deficiency ... Loss (without anaemia ... Bleeding, Edema, Celiac ... Inflammatory Disease (IBD ... , cancer) #Iron
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
→ Refer to hematology ... for workup, including ... hemolysis, deficiency anemia ... Vasculitides, IBD ... , Celiac disease
Irritable Bowel Syndrome (IBS) - Diagnosis and Workup Summary Use a positive diagnostic strategy with minimal testing.
Diagnosis and Workup ... - Rule out celiac ... and Hepatology ... Syndrome #Diagnosis #workup ... #gastroenterology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
formed or don’t work ... skin that are caused ... rings of excess iron ... Workup: • Complete ... Syndromes #diagnosis #hematology
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