27 results
Systemic Sclerosis (Scleroderma)
Multi-system autoimmune disease characterized by vasculopathy and progressive fibrosis of skin and internal organs
3
Systemic Sclerosis ... autoimmune disease ... #SSc #rheumatology ... #diagnosis #signs ... #workup
Antinuclear Antibodies (ANA)
ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
context of other symptoms ... sclerosis/scleroderma ... sclerosis/scleroderma ... ANA #patterns #rheumatology ... #diagnosis #differential
Primary Biliary Cirrhosis - Diagnosis Algorithm
Symptoms: Fatigue, Pruritus, Right upper quadrant discomfort
Signs: Jaundice, Xanthelasmata, Hepatomegaly
Associated history:
Algorithm Symptoms ... quadrant discomfort Signs ... of autoimmune disease ... PBC if 2/3 criteria ... #Algorithm #hepatology
Systemic Lupus Erythematosus - Diagnosis
Manifestations:
 - Arthritis 69%
 - Malar rash 40%
 - Fever 36%
 -
Systemic Lupus Erythematosus ... malignancies, Multiple sclerosis ... autoantibodies #signs ... #symptoms #mimickers ... rheumatology
Multiple Sclerosis - Summary

Multiple Sclerosis (MS) is an autoimmune-mediated neurodegenerative disease of the central nervous system
neurodegenerative disease ... central nervous system ... Signs and symptoms ... criteria for MS ... 85% of pts) → Enter
Eosinophil Disorders Testing Algorithm
INDICATIONS FOR TESTING:
 • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
Disorders Testing Algorithm ... evaluation or workup ... organ-specific signs ... #Differential # ... diagnosis #hematology
Causes of Dizziness - Vertigo - Differential Diagnosis Algorithm
True Vertigo - Illusion of Rotary Movement
Peripheral Vestibular
Diagnosis Algorithm ... • Meniere's Disease ... /signs, bidirectional ... • Multiple sclerosis ... #Diagnosis #Algorithm
Combination of Skin Findings and Arthritis in Pediatrics Patient - Differential Diagnosis
Malar rash: 
 • A
Diagnosis Malar ... with a lighter center ... migrans: • Target sign ... Suggestive of systemic ... #diagnosis #peds
Restrictive Cardiomyopathy - Diagnosis and Causes
Clinical: Dyspnea, Exercise Intolerance, ↑ "Right Sided-Symptoms" (ascites, hepatomegaly, ↑↑peripheral edema)
Physical
↑ "Right Sided-Symptoms ... Cardiomyopathy, Systemic ... Sclerosis, Myofibrillar ... #Causes #differential ... #cardiology #algorithm
Primary Biliary Cirrhosis (PBC) - Summary

PBC Epidemiology:
 • Female:Male 9:1
 • Common European descent
 • Age:
failure PBC Signs ... and Symptoms: ... bile ducts Differential ... cholestasis, Primary sclerosis ... #workup #hepatology