35 results
Mechanisms of Drug-Induced Hyperkalemia 
 • Direct renin inhibitor (Aliskiren)
 • Renin release inhibition (NSAIDs, Beta-Blockers)
• Direct renin inhibitor ... Heparin) • Sodium-channel ... • Increased EC ... differential #diagnosis #pathophysiology ... #pharmacology #
Selective Serotonin Reuptake Inhibitors: Mechanisms and Side Effects
 • Serotonin Syndrome:
   - Autonomic Hyperactivity:
Serotonin Reuptake Inhibitors ... - Cognitive Changes ... #Pathophysiology ... #Pharmacology # ... Psychiatry #Diagnosis #Signs
Serotonin-Norepinephrine Reuptake Inhibitors(SNRIs): Mechanisms and Side Effects

Withdrawal: Dizziness, Diarrhea, Insomnia, Nausea, Vomiting
Serotonin Syndrome - Potentially Life
Serotonin-Norepinephrine Reuptake Inhibitors ... - Cognitive Changes ... #Pathophysiology ... #Pharmacology # ... Psychiatry #Diagnosis #Signs
Guideline for Reversal of Antithrombotics in Intracranial Hemorrhage

The table summarizes the recommendations for adult patients on
Hemorrhage The table ... Direct Factor Xa Inhibitors ... Direct Thrombin Inhibitors ... ICH #Management #Pharmacology ... #Table
Diuretic Electrolyte Excretion Effects 
Diuresis, Na+, K+, Mg2+, Ca2+, Cl-, HCO3-, Uric Acid
 - Thiazide Type
Epithelial Sodium Channel ... Carbonic Anhydrase Inhibitor ... electrolytes #effects #pharmacology ... #comparison #table
Heparin, Fondaparinux, and Novel Oral Anticoagulants - Pathophysiology

Anticoagulation with parenteral (intravenous or subcutaneous) and oral anticoagulants
Anticoagulants - Pathophysiology ... heparin (UFH): Inhibits ... conformational changes ... conformational change ... #Pharmacology #Pathophysiology
Medications Used in Hypertensive Emergencies
Vasodilators: Hydralazine, Nitroglycerin, Sodium nitroprusside 
Calcium Channel Blockers: Clevidipine, Nicardipine
ß-Blockers: Esmolol, Labetalol,
nitroprusside Calcium Channel ... Metoprolol ACE Inhibitors ... Management #Treatment #Pharmacology ... #Table
PDE5 inhibitors are usually the drugs of first choice for erectile dysfunction.

PDE5 inhibitors enhance an erection that is
PDE5 inhibitors ... PDE5 inhibitors  ... with caution - e.g ... #pharmacology #comparison ... dosing #drugs #table
Drugs that Impair Renal Potassium Excretion 

Decreased ENaC channel function: Amiloride, Triamterene, Pentamidine
Decreased Aldosterone Synthesis: Heparin,
Decreased ENaC channel ... Aldosterone Release: ACE inhibitors ... #Hyperkalemia #Pathophysiology ... #Pharmacology #
Immune Reactions and Immunosuppressant Drugs

Glucocorticoids - Inhibition of cytokine synthesis, e.g., IL-1, IL-2
Muromonab-CD3 - Monoclonal antibody
Calcineurin
cytokine synthesis, e.g ... antibody Calcineurin inhibitors ... Immunosuppressant #Drugs #Pharmacology ... #Pathophysiology