10 results
Basophilia - Differential Diagnosis Framework

Basophils < 1% of the total white blood cell count
Basophils function similarly
Basophilia - Differential ... the total white blood ... cell count Basophils ... : • Chronic myeloid ... Diagnosis #causes #hematology
Blood Disorders - Markers and Differential Diagnosis Algorithm 
Acute
 • Myloid (AML) - CD13, CD33, CD34,
Blood Disorders ... - Markers and Differential ... - CD7, CD3 Chronic ... @AmyChung #Blood ... #Disorders #hematology
Causes of Thrombocytosis - Differential Diagnosis
Secondary Thrombocytosis (a.k.a Reactive Thrombocytosis):
 • Acute infection
 • Solid organ
- Differential ... ): • Acute infection ... inflammatory disorders ... myeloid leukemia (CML ... Diagnosis #Causes #hematology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
→ Refer to hematology ... : Acute blood loss ... : Chronic infections ... post-splenectomy, Exercise, Allergic ... Diagnosis #Algorithm #hematology
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
Malaise, bleeding, infections ... eosinophilia, basophilia ... , and thrombocytosis ... or functional neutropenia ... #Leukemia #Hematology
Eosinophil Disorders Testing Algorithm
INDICATIONS FOR TESTING:
 • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
• Peripheral blood ... common causes are asthma ... , allergy, drug ... #Algorithm #Differential ... #diagnosis #hematology
Causes of Neutropenia - Differential Diagnosis
Neonate:
 - Infection - by far the most common cause
 -
- Differential ... including white blood ... cell aplasia DOI ... #differential # ... diagnosis #causes #hematology
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
weeks without infection ... lymphoproliferative disorders ... Lymphocytosis: Absolute blood ... Cytopenias: • Neutropenia ... workup #oncology #hematology
Approach to Elevated Tryptase - Differential Diagnosis Framework

The DDx of elevated tryptase can be broken down
Eosinophilic GI Disorders ... • Parasitic infections ... Causes: • Mast cell ... #Diagnosis #hematology ... #allergy
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
are a group of disorders ... Marrow Failure • Chronic ... Myeloproliferative Disease • Neutropenia ... count with differential ... Syndromes #diagnosis #hematology