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differential oncology aplastic approach bruising elevatedmcv folate folicacid macrocytic macrocytosis management mcv mds myelodysplasia myelodysplastic neutropenia normocytic nutrition platelet syndromes
Causes of Neutropenia with Pancytopenia - Differential Diagnosis Algorithm Sequestration: • Splenomegaly Marrow Infiltration: • Hematologic and non-hematologic
with Pancytopenia ... Toxins • Aplastic Anemia ... Myelodysplasia Nutritional deficiency ... #Algorithm #Causes ... #Hematology
Causes of Anemia by Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Low Mean Corpuscular Volume (<80
Causes of Anemia ... 80-100 fL) • Bleeding ... #MCV #Classification ... #Algorithm #Causes ... #Hematology
Causes of Bleeding / Bruising - Differential Diagnosis Algorithm Thrombocytopenia - Quantitative Defect • Decreased Production •
Causes of Bleeding ... - Differential Diagnosis ... Algorithm Thrombocytopenia ... #Algorithm #Causes ... #Hematology
Overall Approach to Anemia - Differential Diagnosis Algorithm Blood Loss • Acute Bleed - Normocytic / Normochromic
- Differential Diagnosis ... Algorithm Blood ... #Classification ... #Algorithm #Causes ... #Hematology
Causes of Thrombocytosis - Differential Diagnosis Algorithm Spurious: • Artifact (redo CBC) Autonomous: • Essential thrombocytosis • Polycythemia
• Rheumatic disorders ... malignancy • Iron deficiency ... anemia #Thrombocytosis ... #Algorithm #Causes ... #Hematology
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Normal Blood Smear •
Causes of Anemia ... Pregnancy) - Low ... • Small Bowel Disorder ... #Algorithm #Causes ... #Hematology
Causes of Anemia with Normal Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Decreased WBCs - Decreased/NormaI
Causes of Anemia ... Hypothyroid • Pregnancy ... • Early Iron Deficiency ... #Algorithm #Causes ... #Hematology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
- Differential Diagnosis ... - History of bleeding ... changes), high MCV anemia ... ITP, unexplained pancytopenia ... #hematology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
ecchymoses, mucosal bleeding ... and petechiae Causes ... , GATA2 deficiency ... #oncology #hematology ... #diagnosis #management
Etiologies of Folate Deficiency • Decreased dietary intake - uncommon in this era • Increased requirements
Patients who are pregnant ... have hemolytic anemia ... folate that can cause ... #differential #diagnosis ... #hematology #nutrition
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