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rheumatology differential management autoantibodies ana antinuclear clinical cold comparison disease erythematosus lupus myositis systemic agglutinin anemia autoimmune behcet bloodsmear borrelia
Autoantibodies and their Disease Associations ANA - Non-specific; common in SLE, autoimmune hepatitis Anti-CCP, Rheumatoid factor - RA Anti-dsDNA
their Disease Associations ... Autoantibodies #Associations ... #diseases #diagnosis ... #table #rheumatology ... #antibodies
Autoantibodies in Rheumatology • Lupus (SLE): ANA (anti-nuclear antibody), dsDNA (double-stranded DNA), Anti-Smith, Anti-Ro (SSA) and
others (RNP, aPL antibodies ... Antiphospholipid Antibody Syndrome ... LAC) • Sjogren Syndrome ... #diagnosis #associations ... #table
Myositis Specific Antibodies (MSAs) Dermatomyositis: MDA5, TIF1y, NXP2, Mi-2, SAE Anti-Synthetase Syndrome: Jo-1, PL7, PL12, EJ, OJ Immune Mediated
Myositis Specific Antibodies ... Anti-Synthetase Syndrome ... MSAs #clinical #diagnosis ... #rheumatology # ... table
Connective tissue disease-associated interstitial lung diseases LIP: lymphoid interstitial pneumonia. NSIP: nonspecific interstitial pneumonia. OP: organizing pneumonia.
PSS: Sjogren syndrome ... LungDisease #CTILD #Diagnosis ... Differential #Comparison #Table ... #Pulmonary #Rheumatology ... #Associations
Antinuclear antibodies and Systemic lupus Anti-dsDNA 60-80% Association with disease activity (when with Farr assay) and lupus nephritis. Can
Antinuclear antibodies ... SLE-SSc-AlM overlap syndromes ... erythematosus #diagnosis ... #rheumatology # ... table #ANA
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
Cold Sensitive Antibodies ... Donath-Landsteiner Antibodies ... Cold Agglutinin Syndrome ... Donath-Landsteiner (IgG) antibodies ... hemolytic #anemia #hematology
Cold Urticaria Prevalence - 0.05% in the population Disease onset - Mostly 2nd to 4th decades of life Causes
Causes and clinical associations ... and duration of symptoms ... angioedema Other symptoms ... #rheumatology # ... comparison #table
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
context of other symptoms ... SLE), Sjogren's Syndrome ... Arthritis, Sjögren Syndrome ... ANA #patterns #rheumatology ... #diagnosis #differential
Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS) Definition: • Severe adverse drug reaction, characterized by
extensive skin rash in association ... Symptoms: • The ... Criteria for Diagnosis ... SinaiBmoreIMRes #DRESS #Syndrome ... #dermatology #diagnosis
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
Asia • HLA-B51 association ... meningitis), MCC CNS symptoms ... ) Differential Diagnosis ... #signs #symptoms ... #rheumatology #
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