918 results
Immune Checkpoint Inhibitors

PD-1 inhibitors
 - Nivolumab
 - Pembrolizumab
CTLA-4 inhibitors
 - Ipilimumab
 - Tremelimumab
PD-L1 inhibitors
 - Atezolizumab
Immune Checkpoint ... Durvalumab #Immune ... #Checkpoint #Inhibitors ... #Targets #Pathophysiology
Immune-related adverse events (irAE) of  immune checkpoint inhibitors (ICI) 

- By Antoine Briantais 
Dr. Benjamin
Immune-related adverse ... events (irAE) of immune ... checkpoint inhibitors
Check point inhibitors and Side Effects - Immune-related adverse events (IRAEs)

What are the side effects?
 -
Side Effects - Immune-related ... - Immune-related ... - Most immune-related ... by stopping the checkpoint
Pathophysiology of Hypocomplementemic Urticarial Vasculitis

C1q/anti-C1q antibiody ->
Immune Complex Formation - Complement Pathway Activation (C3a and C5a)
Pathophysiology ... antibiody -> Immune ... cells -> Incr Immune ... Vasculitis #HUV #Pathophysiology
Checkpoint Inhibitors: Immune-Related Adverse Events (irAEs)

#Checkpoint #Inhibitors #SideEffects #AdverseEffects #irAEs #diagnosis #Incidence
Checkpoint Inhibitors ... : Immune-Related ... Events (irAEs) #Checkpoint
Myocarditis 

5 Principles of
Myocarditis:
1. Build clinical suspicion
2. Decide on EMBx
3. Manage acute cardiac injury
4. Manage chronic
anti-metabolite - Immune ... Checkpoint Inhibitors
Immune Checkpoint–Blocking Antibodies Approved by the Food and Drug Administration #Pharm #Honc #Checkpoint #Blockade #FDA #Antibodies
Immune Checkpoint–Blocking ... #Pharm #Honc #Checkpoint
NSAIDS and their effects on the Kidney - Pathophysiology

Arachidonic Acid metabolites into alternative pathways that modify
on the Kidney - Pathophysiology ... pathways that modify immune ... Idiosyncratic immune ... nephrology #Effects #pathophysiology
Rapidly Progressive Glomerulonephritis (RPGN) 
 - Loss of kidney function over a short period of tirne
Bowman's space) Immune-Complex ... • Presence of immune ... deposits Pauci-lmmune ... • Minimal immune
Summary of Approach to Patients on Immune Checkpoint Inhibitors - Symptom Staging and Management for Common
to Patients on Immune ... Checkpoint Inhibitors ... Pneumonitis, Rash) #Checkpoint