564 results
Immune-related adverse events (irAE) of  immune checkpoint inhibitors (ICI) 

- By Antoine Briantais 
Dr. Benjamin
checkpoint inhibitors (ICI ... TerrierBen #irAE #ICI ... #CheckpointInhibitors
Intracranial Hemorrhage (ICH) and Increased Intracranial Pressure (ICP) - Pathophysiology
ICH Management:
1. Manage Blood Pressure
  •
Pathophysiology ICH ... • Spontaneous ICH ... blood volume and ICP ... if needed ICP ... High ICP: 20.
Decubitus Ulcer - Diagram of stages. A, Stage I pressure ulcer. B, Stage II pressure ulcer.
B, Stage II pressure ... C, Stage III pressure ... Ulcers #Stages #III
Antiarrhythmics - Vaughan Williams Classification
Class I (Ia, Ib, Ic) - Na+ Channel Blockade
 • Slows depolarization
Class I (Ia, Ib, Ic ... complex Class II ... interval Class III
Antiarrhythmic Drug Classes 
IA: "Police Department Questions 
IB: Liquored Man 
IC: For Peeing, 
Ill: After Drinking
Liquored Man IC ... Lidocaine Mexiletine IC ... Propafenone III
Unicondylar proximal phalangeal fractures can be classified into four basic groups: oblique volar (I), long sagittal
long sagittal (II ... dorsal coronal(III
Approach to ECGs
Check
 - Age, gender, name
 - 25mm/s; 10mm/mV
 - 1mm = 40ms; 0.1 mV
Rate
(2) P+ve in l, II ... QRS +ve in I, II ... V-pacemaker, ↑K, ICD ... congenital, MI, high ICP
Important Blood Pressure Targets in the ED
Subarachnoid Hemorrhage: 
    SBP < 140 -
raised ICP: MAP ... 80 Spontaneous ICH ... raised ICP: MAP ... raised ICP: MAP
Capnography
Measurement of exhaled carbon dioxide can be used to confirm ETT placement, for safer procedural sedation,
Downsloping phase III ... Prolonged phase II ... /III: bronchospasm ... Dimorphic phase II ... /III: right mainstem
Forrest Classification for Peptic Ulcer Bleeding
Rebleeding risks are without endoscopic intervention
1a - Spurting Bleed - 60-100%
30% Re-bleeding IIc ... 10% Re-bleeding III