15 results
Anti-infective stewardship, including tips for using anti-infectives wisely, criteria for stepdown from IV to PO dosage
including tips for using ... dosage forms and conversion ... #pharmacology #antibiotics ... table #treatment #drugs
Causes of Neutropenia with Pancytopenia - Differential Diagnosis Algorithm
Sequestration:
 • Splenomegaly
Marrow Infiltration:
 • Hematologic and non-hematologic
- Differential Diagnosis ... suppression: • Chemotherapy ... Radiation • Drugs ... Toxins • Aplastic Anemia ... Algorithm #Causes #Hematology
Causes of Thrombocytopenia - Differential Diagnosis Algorithm
 
Decreased Megakaryopoiesis
 • Aplastic Anemia
 • Toxic Damage (e.g.
- Differential Diagnosis ... Megakaryopoiesis • Aplastic Anemia ... Chemotherapy) ... methotrexate) • Drugs ... anti-HLA antibodies Drugs
Red Blood Cell (RBC) Morphology
Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),
Iron deficiency anemia ... Disease, MDS, Chemotherapy ... disorders, Oxidative drugs ... #differential #diagnosis ... #hematology #microscopy
Reticulocyte Production Index = (Retic %) x (Hct / 45) / Maturation Factor
The maturation factor is
Index < 2: • Anemia ... suppression (e.g. drugs ... , chemotherapy, ... Production #Index #hematology ... #diagnosis #calculation
Managing warfarin INR

Warfarin dosage must be individualized according to the patient's response to the drug, and
response to the drug ... management #algorithm #pharmacology ... #decisionaid #cardiology ... #hematology #warfarin ... #dosing
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Dyskeratosis congenita • Drugs ... - Cytotoxic drugs ... /Chemotherapy ... - β-lactam antibiotics ... #diagnosis #management
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes
Intravascular Hemolysis:
 • Mechanical Trauma (Microangiopathic hemolytic anemia):
Diagnostic Framework ... Microangiopathic hemolytic anemia ... infection) - Drugs ... (Beta lactam antibiotics ... #hematology #anemia
Pediatric Vomiting - Gastrointestinal and Systemic Causes - Differential Diagnosis Algorithm
Hepatobiliary:
 • Acute Hepatitis
 • Acute
- Differential Diagnosis ... Diabetes/ DKA • Uremia ... Tract Infection Drugs ... /Toxins: • Chemotherapy ... • Antibiotics
Hyperkalemia - Differential Diagnosis Framework

PseudoHyperkalemia:
 • Lab error
 • Traumatic venipuncture
 • Hemolysis, thrombocytosis, leukocytosis
 •
- Differential Diagnosis ... Clenching of fist during ... controlled DM • Chemotherapy ... reactions Common Drugs ... Beta blockers • Antibiotics