14 results
Causes of Neutropenia with Pancytopenia - Differential Diagnosis Algorithm
Sequestration:
 • Splenomegaly
Marrow Infiltration:
 • Hematologic and non-hematologic
- Differential Diagnosis ... suppression: • Chemotherapy ... Radiation • Drugs ... • Toxins • Aplastic ... Algorithm #Causes #Hematology
Causes of Thrombocytopenia - Differential Diagnosis Algorithm
 
Decreased Megakaryopoiesis
 • Aplastic Anemia
 • Toxic Damage (e.g.
Megakaryopoiesis • Aplastic ... Chemotherapy) ... methotrexate) • Drugs ... anti-HLA antibodies Drugs ... Algorithm #Causes #Hematology
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Dyskeratosis congenita • Drugs ... - Cytotoxic drugs ... /Chemotherapy ... - β-lactam antibiotics ... Anemia #oncology #hematology
Managing warfarin INR

Warfarin dosage must be individualized according to the patient's response to the drug, and
response to the drug ... management #algorithm #pharmacology ... #decisionaid #cardiology ... #hematology #warfarin ... #dosing
Hair Loss (Alopecia) - General (Diffuse and Focal) Differential Diagnosis Algorithm

DIFFUSE
Scarring - Irreversible-biopsy required
 • Lupus
Effluvium • Chemotherapy ... Vitamin A Excess - Drugs ... • Hyperthyroid drugs ... Follicularis • Aplasia ... HairLoss #Alopecia #dermatology
Reticulocyte Production Index = (Retic %) x (Hct / 45) / Maturation Factor
The maturation factor is
marrow failure: Aplastic ... suppression (e.g. drugs ... , chemotherapy, ... Production #Index #hematology ... #differential #diagnosis
Hyperkalemia - Differential Diagnosis Framework

PseudoHyperkalemia:
 • Lab error
 • Traumatic venipuncture
 • Hemolysis, thrombocytosis, leukocytosis
 •
- Differential Diagnosis ... phlebotomy High ... controlled DM • Chemotherapy ... reactions Common Drugs ... Beta blockers • Antibiotics
Causes of Pseudocellulitis - Differential Diagnosis Framework for Cellulitis Mimics

Cellulitis: Deep skin and subcutaneous fat infection

Pseudo
avoid unnecessary antibiotics ... inappropriate antibiotic ... Misdiagnosis as high ... Pseudocellulitis: • Drug ... mimickers #Causes #dermatology
Allopecia - Differential Diagnosis Framework for Hair Loss

Localized / Focal Hair Loss Pattern:
 • Scarring Alopecia:
Alopecia mucinosa, Aplasia ... /Cytotoxic Drugs ... deficiency • Drugs ... thallium • Drugs ... #dermatology #Hairloss
Hyperkalemia - Differential Diagnosis Framework

PseudoHyperkalemia:
 • Lab error
 • Traumatic venipuncture
 • Hemolysis, thrombocytosis, leukocytosis
 •
- Differential Diagnosis ... phlebotomy High ... controlled DM • Chemotherapy ... reactions Common Drugs ... Beta blockers • Antibiotics