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management hematology syndrome differential nephrology disease algorithm cancer leukemia table workup aki arthritis causes chronic classification cll dermatology hemophagocytic hlh
Oncologic Emergencies - Differential Diagnosis Framework HEMATOLOGIC ONCOLOGIC EMERGENCIES: Hyperviscosity Syndrome: • Spontaneous bleeding • Shortness of breath
- Differential Diagnosis ... of breath • Neurologic ... Hoarseness • Chest and ... shoulder pain, ... #differential #diagnosis
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
and Management ... and risk-stratification ... only curative treatment ... #Management #treatment ... #hematology #oncology
(DOAC interactions) Cancer-treatment specific inducers (↑) and inhibitors (↓) of cytochrome p450 CYP3A4 and P-glycoprotein. DOACs are substrates
interactions) Cancer-treatment ... Rivaroxaban and ... inducers #inhibitors #Chemotherapy ... #Oncology #Hematology ... Interactions #Table #Pharmacology
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
minimal tumor burden Diagnosis ... benefit of immediate chemotherapy ... lymphadenopathy and ... Lymphocytic #Leukemia #oncology ... #hematology #hemeonc
Acute Kidney Injury (AKI) in Patients with Cancer Cancer Related • Hypercalcemia • Intravenous contrast •
malignancies Treatment ... Methotrexate • AIN ... #AKI #Cancer #Oncology ... #Differential #Diagnosis ... Classification #Nephrology
THE LIMPING OR NON-WEIGHT BEARING CHILD PATHWAY RED FLAGS - In all cases there are specific markers which
Malignancy - Night pain ... splenomegaly, abnormal neurology ... , back pain Haematology ... cell disease Rheumatology ... Peds #Pediatrics #Diagnosis
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Triggers: ATRA treatment ... effusions, weight gain ... Renal Failure Treatment ... #management #hematology ... #oncology
Tolosa-Hunt Syndrome What? • Unilateral orbital/retrobulbar pain • Paresis of the cranial nerves Ill, IV, VI •
orbital/retrobulbar pain ... Involvement of V1, V2 and ... or orbit (MRI) Treatment ... Syndrome #TolosaHunt #neurology ... #diagnosis
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
permeability Diagnosis ... Erythematosus #SLE #CNS #neurology ... #rheumatology # ... cerebritis #diagnosis ... #management #treatment
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Auto-amplification loop Diagnosis ... Unknown cause Treatment ... Anti-infectious, chemotherapy ... #management #treatment ... #summary #rheumatology
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