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diagnosis hematology differential causes atlas rbc workup blood bloodcell endocrinology enlarged gout hyperuricemia key markers mds mentzerindex microcytic microscopy myelodysplasia
Blood Disorders - Markers and Differential Diagnosis Algorithm Acute • Myloid (AML) - CD13, CD33, CD34,
- Abnormal morphology ... Pseudo Pelger-Huet, Macrocytic ... anemia - ... • Lymphoid (CLL ... #hematology #Markers
Red Blood Cell (RBC) Morphology Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),
RBC) Morphology ... (sometimes) Macrocytic ... Unstable hemoglobin disorders ... BloodCell #RBC #Morphology ... differential #diagnosis #hematology
Red Blood Cell (RBC) Morphology Atlas • Microcytic - Iron-deficiency anemia, Thalassemia, Sideroblastic anemia, Lead poisoning
RBC) Morphology ... Lead poisoning • Macrocytic ... spherocytosis, Hemolytic ... Schistocytes - Hemolytic ... #differential #hematology
Anemia Diagnostic Algorithm Mean corpuscular (cell) volume (MCV): Average RBC size. Under 80 = microcytic. Between 80-95
Anemia Diagnostic ... Algorithm Mean ... acute blood loss, hemolysis ... (BM) ablative disorders ... #Workup #Hematology
Hyperuricemia - Differential Diagnosis Algorithm Primary - Over-production • Increased turnover of nucleotides Primary
Differential Diagnosis Algorithm ... Lymphoproliferative Disorders ... (CML) - Hemolytic ... Anemia - Others ... Differential #Diagnosis #Algorithm
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia ... Consider sickle cell ... other reproducible morphologic ... Consider RBC membrane disorder ... #workup #hematology
Causes of Thrombocytosis - Differential Diagnosis Secondary Thrombocytosis (a.k.a Reactive Thrombocytosis): • Acute infection • Solid organ
malignancies • Anemia ... iron deficiency, hemolysis ... Chronic inflammatory disorders ... Chronic myeloid leukemia ... (CML) - Dr.
Causes of Splenomegaly - Differential Diagnosis Algorithm Infectious • Bacterial • Viral (EBV) • Parasitic • Fungal Congestive
• Lymphoma • Leukemia ... Myeloproliferative disorders ... Serum Sickness Hemolytic ... Disease • Sickle Cell ... #Causes #Hematology
Hematology Algorithms Anemia is described as a reduction in the proportion of the red blood cells.
Hematology Algorithms ... corpuscular volume into microcytic ... MCV 80-100 fl) & macrocytic ... involves production disorders ... that involves disorders
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
are a group of disorders ... common cytopenia: Macrocytic ... Chronic Myelogenous Leukemia ... Leukemia • Idiopathic ... Neutropenia • Platelet Disorders
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