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diagnosis hematology differential causes algorithm management workup iron hemolytic clinical comparison laboratory oncology classification hemolysis hepatology macrocytic microscopy nutrition secondary
Peripheral Blood Smear Analysis Hypochromia Megaloblastic Anemia Schistocytes: Microangiopathic hemolytic anemia (e.g. DIC, TTP, HUS) Microspherocytes: Autoimmune hemolytic anemia Sickled red
Peripheral Blood ... Megaloblastic Anemia ... Bite cells: G6PD deficiency ... #Peripheral #Blood ... Smear #Analysis #hematology
Red Blood Cell (RBC) Morphology Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),
Red Blood Cell ( ... RBC: Pyridoxine deficiency ... Thalassemia, Iron deficiency ... disease, McLeod blood ... differential #diagnosis #hematology
Red Blood Cell (RBC) Morphology Atlas • Microcytic - Iron-deficiency anemia, Thalassemia, Sideroblastic anemia, Lead poisoning
Red Blood Cell ( ... Microcytic - Iron-deficiency ... Thalassemia, Iron-deficiency ... cells - G-6-PD deficiency ... #differential #hematology
Diagnostic Framework for Anemia (Morphological Approach - MCV) Low MCV - <80fL - "Microcytic" • Iron deficiency
Microcytic" • Iron deficiency ... disease, Acute blood ... Megaloblastic: Vitamin B12 deficiency ... , Folate deficiency ... diagnosis #causes #hematology
Anemia - Underproduction Diagnostic Algorithm - Iron deficiency anemia - Anemia of chronic inflammation - Anemia
Anemia - Underproduction ... Algorithm - Iron deficiency ... anemia - Anemia ... and/or folate deficiency ... Underproduction #Algorithm #hematology
Reticulocyte Production Index = (Retic %) x (Hct / 45) / Maturation Factor The maturation factor is
the peripheral blood ... deficiencies: Iron deficiency ... > 3: • Acute blood ... , G6PD deficiency ... Production #Index #hematology
Overall Approach to Anemia - Differential Diagnosis Algorithm Blood Loss • Acute Bleed - Normocytic / Normochromic
Overall Approach to Anemia ... Diagnosis Algorithm Blood ... Reticulocytes • Iron Deficiency ... • B12/Folate Deficiency ... Algorithm #Causes #Hematology
Iron Deficiency Anemia - Differential Diagnosis Algorithm Labs: Ferritin, iron, transferrin, TIBC, TSAT, sTfR • Blood loss:
Iron Deficiency ... Anemia - Differential ... TSAT, sTfR • Blood ... #Anemia #Differential ... Algorithm #ferritin #hematology
Thrombocytosis - Differential Diagnosis Platelet Count > 450 Reactive: • Anemia/blood loss (Fe deficiency) • Infection/Sepsis • Non-infectious
Reactive: • Anemia ... /blood loss (Fe ... deficiency) • ... causes #Platelets #hematology
Iron Deficiency Anemia vs Anemia of Chronic Disease - Laboratory Testing SUMMARY: - RDW, FEP, serum iron,
Iron Deficiency ... Anemia vs Anemia ... TIBC-specific for iron deficiency ... #Anemia #Chronic ... Testing #Comparison #Table
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