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diagnosis differential lupus management rheumatology sle causes erythematosus nephrology common criteria cvid dermatology disorders eularacr hypogammaglobulinemia immunodeficiency immunology lad lymphadenopathy
Lupus Nephritis Primer Class I - Minimal Mesangial Class II - Mesangial Proliferative Class Ill - Focal Proliferative Class IV
Lupus Nephritis ... Primer Class I - ... Proliferative Class ... IV - Diffuse Proliferative ... #SLE #Classification
Management of Lupus Nephritis Lupus nephritis (LN) in 10 to 40% of SLE Hallmark = proteinuria 20.5 g/g
: • Class I - ... mesangial LN • Class ... proliferative LN • Class ... chronic lesions • Class ... Membranous LN • Class
EULAR/ACR Classification Criteria for Systemic Lupus Erythematosus Clinical Domains: • Constitutional domain: Fever • Cutaneous domain: Non-scarring
EULAR/ACR Classification ... Criteria for Systemic ... pericarditis • Hematologic ... > 0.5 g/24 hr, Class ... , Class Ill or IV
Causes of Diffuse Lymphadenopathy - Differential Diagnosis Algorithm Reactive: - Systemic Inflammatory •
Causes of Diffuse ... Differential Diagnosis Algorithm ... Reactive: - Systemic ... Inflammatory • Systemic ... #Causes #Hematology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... Skin Disease Classification ... pneumonitis • Diffuse ... enteropathy, and diffuse ... Neuropsychiatric systemic
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
with lymphatic system ... are present • Classic ... lymphadenopathy more diffuse ... Lymphoproliferative #Disorders #Classification ... pathophysiology #Hematology
Nail Disorders secondary to Systemic Diseases Nail Fold Abnormality • SLE • Scleroderma • Dermatomyositis Koilonychia - Spoon-shaped
Disorders secondary to Systemic ... discoloration) • Nephrotic ... #Secondary #dermatology ... Differential #Diagnosis #Algorithm ... #causes
Common Variable Immunodeficiency (CVID) What? CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
CT: • Ground-glass ... hemolytic anemia) • Systemic ... DDX - Other causes ... hypogammaglobulinemia: • Nephrotic ... hypogammaglobulinemia #immunology #hematology
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