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diagnosis differential rheumatology causes allergy erythematosus hypersensitivity pathophysiology sle types comparison criteria dermatology disorders eularacr high hyperkalemia lad lymphadenopathy lymphomas
EULAR/ACR Classification Criteria for Systemic Lupus Erythematosus Clinical Domains: • Constitutional domain: Fever • Cutaneous domain: Non-scarring
EULAR/ACR Classification ... Criteria for Systemic ... > 0.5 g/24 hr, Class ... , Class Ill or IV ... #EULARACR #Classification
Causes of Diffuse Lymphadenopathy - Differential Diagnosis Algorithm Reactive: - Systemic Inflammatory •
Causes of Diffuse ... Differential Diagnosis Algorithm ... Reactive: - Systemic ... Lupus Erythematosus ... #Causes #Hematology
Management of Lupus Nephritis Lupus nephritis (LN) in 10 to 40% of SLE Hallmark = proteinuria 20.5 g/g
severity (ISN/RPS classification ... by 12 months Classification ... IV - Diffuse LN ... glomeruli) Diffuse ... treatment #management #rheumatology
Vesiculobullous Skin Rash - Differential Diagnosis Algorithm Vesicles Fragile/EasiIy Ruptured - Intraepidermal blisters, possibly crusts/erosions - Inflammatory
Differential Diagnosis Algorithm ... Bullous impetigo - Reaction ... • Bullous systemic ... lupus erythematous ... #causes
Summary table of types of hypersensitivity reactions. Type 1 - Mediators: lgE - Antigen Form: Soluble
Summary table of ... Allergen-specific lgE causes ... glomerulonephritis, Systemic ... lupus erythematosus ... #classification
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
with lymphatic system ... are present • Classic ... lymphadenopathy more diffuse ... Lymphoproliferative #Disorders #Classification ... pathophysiology #Hematology
Hypersensitivity Types and Their Mechanisms Type I - lgE - Soluble antigen - Allergen-specific lgE antibodies bind
- Local and systemic ... lupus erythematosus ... Hypersensitivity #Types #Classification ... Allergy #Diagnosis #Reactions ... #Table
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... Skin Disease Classification ... pneumonitis • Diffuse ... enteropathy, and diffuse ... Neuropsychiatric systemic
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
tract, and often causes ... inflammation Others: • Lupus ... lupus erythematosus ... disease, drug reactions ... #classification
Causes of Hyperkalemia l. Pseudohyperkalemia A Cellular efflux; thrombocytosis, erythrocytosis, leukocytosis, in vitro hemolysis B.
Causes of Hyperkalemia ... neuromuscular injury, disuse ... lupus erythematosus ... High #Potassium #Classification ... #Causes
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